التفاصيل البيبلوغرافية
| العنوان: |
Optimization of neutralization assay against CHIKV. |
| المؤلفون: |
Gómez-Suárez, Alexis, Salinas-Trujano, Juana, González-González, Edith, Pérez-Tapia, Sonia M., Almagro, Juan C. |
| المصدر: |
Veterinaria México OA; 2024 Special Issue, Vol. 11, p90-90, 1p |
| مصطلحات موضوعية: |
MICROBIOLOGICAL assay, CHIKUNGUNYA virus |
| مستخلص: |
Chikungunya virus (CHIKV) is a virus transmitted by Aedes mosquitoes, producing a disease that causes fever and joint pain. Quantification of neutralizing antibodies against Chikungunya virus can be crucial to evaluate possible treatments, vaccines and to understand the immune response. The process of optimizing the neutralization assay usually involves several steps; from selecting the appropriate viral and cellular strains, as well as the assay incubation conditions and time to observe the neutralizing effect of the antibodies on the cell monolayer, measuring the reproducibility and specificity between the positive and negative controls used in the assay repeats, determining the functional range and sensitivity of the assay. This work reports the optimization of the neutralization assay against CHIKV. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |