التفاصيل البيبلوغرافية
| العنوان: |
HYDROGEL INNOVATIONS IN DIABETES CARE: ADVANCED DRUG DELIVERY AND FLEXIBLE DIAGNOSIS TECHNIQUES. |
| المؤلفون: |
Singh, Mahaveer, Tripathi, Kamalesh, Goel, Neha, Mollik, Mohammed Sofiqul, Chakraborthy, Gunosindhu, Mishra, Avinash Kumar Vivekanand, Krosuri, Pavankumar, Bhavsar, Devesh Pravinkumar, Singh, Suruchi |
| المصدر: |
Journal of Experimental Zoology India; Jul2024, Vol. 27 Issue 2, p2119-2128, 10p |
| مصطلحات موضوعية: |
POLYMER networks, CONTINUOUS glucose monitoring, GLUCOSE analysis, GLYCEMIC control, INSULIN receptors, DRUG delivery systems, HYPERGLYCEMIA, BLOOD sugar |
| مستخلص: |
Hydrogel-based technologies have emerged as transformative tools in the management of diabetes, offering novel solutions in both drug delivery and diagnostic techniques. Diabetes, a chronic metabolic disorder characterized by elevated blood glucose levels, necessitates precise and consistent therapeutic interventions to mitigate its complications and improve patient outcomes. This abstract explores recent innovations in hydrogel applications tailored for diabetes care, focusing on advanced drug delivery systems and flexible diagnostic techniques. Hydrogels, three-dimensional networks of hydrophilic polymers capable of absorbing and retaining large amounts of water, exhibit properties that make them ideal candidates for biomedical applications. In drug delivery, hydrogels offer controlled release mechanisms that can mimic physiological conditions, enhancing the efficacy of therapeutics such as insulin and GLP-1 receptor agonists. Innovations in this area include stimuliresponsive hydrogels that release drugs in response to changes in glucose levels or other physiological cues, thereby improving glycemic control and patient compliance. Additionally, the development of injectable hydrogel formulations allows for sustained drug release, reducing the frequency of administrations and providing long-term therapeutic benefits. Furthermore, hydrogelbased diagnostic techniques have revolutionized diabetes management by enabling non-invasive and continuous monitoring of glucose levels. Hydrogel-based biosensors offer real-time monitoring capabilities, detecting glucose and other biomarkers through wearable devices or integrated patches. These sensors leverage the biocompatibility and flexibility of hydrogels to adhere comfortably to the skin, ensuring prolonged and accurate monitoring without the discomfort associated with traditional methods. Moreover, advancements in microneedle technology have facilitated minimally invasive glucose monitoring, with hydrogel-based microneedle patches capable of sampling interstitial fluid for glucose analysis. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |