التفاصيل البيبلوغرافية
| العنوان: |
Experimental Susceptibility of Nyssomyia antunesi and Lutzomyia longipalpis (Psychodidae: Phlebotominae) to Leishmania (Viannia) lainsoni and L. (V.) lindenbergi (Trypanosomatidae: Leishmaniinae). |
| المؤلفون: |
Sánchez Uzcátegui, Yetsenia del Valle, Silveira, Fernando Tobias, de Morais, Thais Gouvea, Furtado, Rodrigo Ribeiro, Vasconcelos dos Santos, Thiago, Póvoa, Marinete Marins |
| المصدر: |
Microorganisms; Apr2024, Vol. 12 Issue 4, p809, 13p |
| مصطلحات موضوعية: |
LUTZOMYIA, PSYCHODIDAE, TRYPANOSOMATIDAE, PROMASTIGOTE, SAND flies, LEISHMANIA |
| مستخلص: |
The present work assessed the experimental susceptibility of Nyssomyia antunesi and Lutzomyia longipalpis to Leishmania (Viannia) lainsoni and L. (V.) lindenbergi. A L. (Leishmania) chagasi–Lu. longipalpis combination was used as a susceptible control. Wild-caught Ny. antunesi and laboratory-bred Lu. longipalpis were membrane-fed on blood with a 5 × 106/mL log-phase promastigote culture suspension and dissected on days 2 and 8 post-blood meal (pbm) for analysis focused on the assessment of parasitoses, as well as placement and promastigote morphotyping. Survival curves were constructed. In all combinations, promastigotes were observed on day 8 pbm. For both Leishmania species, in Lu. longipalpis, the presence of parasites was observed up to the stomodeal valve, while in Ny. antunesi, the presence of parasites was observed up to the cardia. There were no significant differences in parasitosis between L. (V.) lainsoni and L. (V.) lindenbergi in either Ny. antunesi or Lu. longipalpis. Six morphological promastigote forms were distinguished in Giemsa-stained gut smears. The survival curves of all combinations decreased and were affected differently by several Lu. longipalpis–parasite combinations, as well with Lu. longipalpis–uninfected blood. These findings stress Lu. longipalpis as experimentally susceptible to Leishmania spp. and suggest the putative susceptibility of Ny. antunesi to L. (V.) lainsoni and L. (V.) lindenbergi. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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