التفاصيل البيبلوغرافية
| العنوان: |
男性不妊症：Klinefelter 症候群の 顕微鏡下精巣内精子採取術について. |
| Alternate Title: |
MALE INFERTILITY : MICRODISSECTION TESTICULAR SPERM EXTRACTION FROM PATIENTS WITH KLINEFELTER'S SYNDROME. (English) |
| المؤلفون: |
原 綾 英, 杉 山 星 哲, 堀 川 雄 平, 上 原 慎 也, 宮 地 禎 幸 |
| المصدر: |
Nishinihon Journal of Urology; Dec2023, Vol. 86 Issue 2, p39-45, 7p |
| مصطلحات موضوعية: |
KLINEFELTER'S syndrome, MALE infertility, INTRACYTOPLASMIC sperm injection, AZOOSPERMIA, INFERTILITY |
| Abstract (English): |
Klinefelter's syndrome (KS) was previously believed to cause absolute male infertility as a representative form of non-obstructive azoospermia. However, it is now possible for individuals with KS to bear children if sperm can be retrieved using microdissection testicular sperm extraction (micro-TESE) for intracytoplasmic sperm injection (ICSI). Moreover, the current success rate of sperm retrieval by micro-TESE in KS patients is higher than that in patients with idiopathic non-obstructive azoospermia, and micro-TESE is indicated for patients with KS. However, the performance of micro-TESE for sperm extraction in KS patients requires special skills due to specific testicular findings. In addition, an appropriate medical environment is needed to address the postoperative reduction of blood testosterone levels. With infertility treatment receiving insurance coverage in FY2022, it is anticipated that the performance of male infertility treatment in general urology departments will increase. Although the opportunities to treat KS have previously been limited, knowledge about KS should be updated. This report reviews the performance of micro-TESE in patients with KS. [ABSTRACT FROM AUTHOR] |
| Abstract (Japanese): |
Klinefelter 症候群 (KS) は, 以前は, 代表的な非閉塞性無精子症疾患として絶対的男性不妊症と考えら れていたが, 顕微鏡下精巣内精子採取術 (Microdissection testicular sperm extraction; micro TESE) で 精子を採取できれば, その後の顕微授精 (intracytoplasmic sperm injection；ICSI）で挙児が見込める時代 になった。また, 現在では, KS の micro TESE の精子採取率は, 特発性非閉塞性無精子症よりも高いこと がわかっており, KS は, micro TESE の良い適応であると考えられている。しかしながら, KS の micro TESE は, その特異的な精巣所見から精子採取に際し熟練を要する。また, 術後のテストステロン低下に 留意した診療環境が必要である。2022 年度から一般不妊治療へ保険適応が拡大され, 一般泌尿器科にとって, 男性不妊症患者の診療機会が徐々に増えることが予想される。今までは診療機会の少なかった KS につい ても update された知識が必要になるだろう。本稿では, KS の micro TESE について概説する。 [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |