التفاصيل البيبلوغرافية
| العنوان: |
Two novel tumours with NTRK2 fusion in the methylation class of extraventricular neurocytomas, including one intraventricular. |
| المؤلفون: |
Uro‐Coste, Emmanuelle, Tauziede‐Espariat, Arnault, Dubucs, Charlotte, Chiforeanu, Dan Christian, Siegfried, Aurore, Nicaise, Yvan, Bauchet, Luc, Riffaud, Laurent, Bielle, Franck, Vasiljevic, Alexandre, Appay, Romain, Evrard, Solène, Varlet, Pascale, Rigau, Valérie |
| المصدر: |
Brain Pathology; May2024, Vol. 34 Issue 3, p1-3, 3p |
| مصطلحات موضوعية: |
TUMORS, METHYLATION |
| مستخلص: |
This article discusses two novel tumors classified as extraventricular neurocytomas (EVN) that were found to have NTRK2 fusions instead of the usual FGFR1 alterations. The first case involved a 23-year-old woman with migraines and epileptic seizures, while the second case involved a 15-year-old girl with intracerebral calcifications. Both cases underwent total removal of the tumors and showed positive staining for synaptophysin and olig2. The study suggests that these findings have implications for diagnosis, therapy, and terminology, and further research is needed to better understand these tumors. [Extracted from the article] |
|
Copyright of Brain Pathology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder