التفاصيل البيبلوغرافية
| العنوان: |
Two Artificial Tears Outbreak-Associated Cases of Extensively Drug-Resistant Pseudomonas aeruginosa Detected Through Whole Genome Sequencing–Based Surveillance. |
| المؤلفون: |
Sundermann, Alexander J, Srinivasa, Vatsala Rangachar, Mills, Emma G, Griffith, Marissa P, Waggle, Kady D, Ayres, Ashley M, Pless, Lora, Snyder, Graham M, Harrison, Lee H, Tyne, Daria Van |
| المصدر: |
Journal of Infectious Diseases; 2/15/2024, Vol. 229 Issue 2, p517-521, 5p |
| مصطلحات موضوعية: |
PSEUDOMONAS aeruginosa, PSEUDOMONAS aeruginosa infections, GENOMES, DRUG resistance in microorganisms, PUBLIC health, WOUND infections |
| مستخلص: |
We describe 2 cases of extensively drug-resistant Pseudomonas aeruginosa infection caused by a strain of public health concern, as it was recently associated with a nationwide outbreak of contaminated artificial tears. Both cases were detected through database review of genomes in the Enhanced Detection System for Hospital-Associated Transmission (EDS-HAT), a routine genome sequencing–based surveillance program. We generated a high-quality reference genome for the outbreak strain from an isolate from our center and examined the mobile elements encoding bla VIM-80 and bla -GES-9 carbapenemases. We used publicly available Pseudomonas aeruginosa genomes to explore the genetic relatedness and antimicrobial resistance genes of the outbreak strain. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |