التفاصيل البيبلوغرافية
| العنوان: |
Local recurrence and metachronous multiple cancers after transoral nonrobotic surgery for pharyngeal and laryngeal squamous cell carcinoma: A retrospective multicenter study. |
| المؤلفون: |
Ushiro, Koji, Watanabe, Yoshiki, Kishimoto, Yo, Kawai, Yoshitaka, Fujimura, Shintaro, Asato, Ryo, Tsujimura, Takashi, Hori, Ryusuke, Kumabe, Yohei, Yasuda, Kaori, Tamaki, Hisanobu, Iki, Takehiro, Kitani, Yoshiharu, Kurata, Keisuke, Kojima, Tsuyoshi, Takata, Kuniaki, Kada, Shinpei, Takebayashi, Shinji, Shinohara, Shogo, Hamaguchi, Kiyomi |
| المصدر: |
Head & Neck; Jan2024, Vol. 46 Issue 1, p118-128, 11p |
| مصطلحات موضوعية: |
SQUAMOUS cell carcinoma, SURGICAL margin, RECTAL surgery, LYMPHATIC metastasis, CARCINOMA in situ, RETROSPECTIVE studies |
| مستخلص: |
Background: Late laryngopharyngeal cancers after transoral surgery include not only local recurrences but also metachronous multiple cancers. Methods: We compared clinical information, surgical outcomes, and late laryngopharyngeal cancers in patients who underwent transoral nonrobotic surgery for laryngopharyngeal squamous cell carcinoma without lymph node metastases between 2015 and 2021 in a multicenter retrospective study. Results: Four hundred and fifty‐seven patients were included. Positive surgical margins were found in 121 patients (26.5%). Twenty‐two patients (4.8%) received additional treatment. Positive horizontal margins of invasive carcinoma (p = 0.003) and positive horizontal margins of carcinoma in situ only (p = 0.032) were independent risk factors for local recurrence, and prior radiotherapy (p = 0.001) for metachronous multiple cancers. Local control was significantly worse without additional treatment (p = 0.049), but there was no significant difference in survival. Conclusions: Patients with positive margins had an increased frequency of local recurrence, but salvage therapy was effective. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |