Academic Journal

Comparison of Initial CT Findings and CO-RADS Stage in COVID-19 Patients with PCR, Inflammation and Coagulation Parameters in Diagnostic and Prognostic Perspectives.

التفاصيل البيبلوغرافية
العنوان: Comparison of Initial CT Findings and CO-RADS Stage in COVID-19 Patients with PCR, Inflammation and Coagulation Parameters in Diagnostic and Prognostic Perspectives.
المؤلفون: AYAZ, ELIF YILDIRIM, COŞKUN, ZAFER ÜNSAL, KAPLAN, MUSTAFA, BULUT, AHMET SAIT, YEŞILDAL, MELIKE, ANKARALI, HANDAN, UYGUN, GÖKHAN, ÇAKLILI, ÖZGE TELCI, UZUNLULU, MEHMET, VAHABOĞLU, HALUK, ODABAŞ, ALI RIZA
المصدر: Journal of the Belgian Society of Radiology; 2022, Vol. 106 Issue 1, p1-10, 10p
مصطلحات موضوعية: COVID-19 testing, COMPUTED tomography, HEALTH outcome assessment, INFLAMMATION, POLYMERASE chain reaction
مستخلص: Objectives: This study aims to determine whether COVID19 patients with different initial reverse transcriptasepolymerase chain reaction (RTPCR), computed tomography (CT) and laboratory findings have different clinical outcomes. Materials and Methods: In this multicenter retrospective cohort study, 895 hospitalized patients with the diagnosis of COVID19 were included. According to the RTPCR positivity and presence of CT findings, the patients were divided into four groups. These groups were compared in terms of mortality and need for intensive care unit (ICU). According to the COVID19 Reporting and Data System (CORADS), all patients' CT images were staged. Multivariate binary logistic regression analysis was used to examine the relationship between CORADS and predictive inflammation and coagulation parameters. Results: RTPCR test positivity was 51.5%, the CT finding was 70.7%, and 49.7% of the patients were in the CORADS 5 stage. The need for ICU and mortality rates was higher in the group with only CT findings compared to the group with only RTPCR positivity, (14.9% vs. 4.0%, p < 0.001; 9.3% vs. 3.3%, p > 0.05; respectively). Mortality was 3.27 times higher in patients with CORADS 4 compared to those with CORADS 1-2. Being in the CORADS 4 stage and LDH were discovered to be the most efficient parameters in determining mortality risk. Conclusion: Performing only the RTPCR test in the initial evaluation of patients in SARSCoV2 infection may lead to overlooking groups that are more at risk for severe disease. The use of a chest CT to perform CORADS staging would be beneficial in terms of providing both diagnostic and prognostic information. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:25148281
DOI:10.5334/jbsr.2714