Academic Journal

Oral health status in patients with inherited epidermolysis bullosa: a comparative multicenter study.

التفاصيل البيبلوغرافية
العنوان: Oral health status in patients with inherited epidermolysis bullosa: a comparative multicenter study.
المؤلفون: Joseph, Clara, Marty, Mathieu, Dridi, Sophie-Myriam, Verhaeghe, Veroniek, Bailleul-Forestier, Isabelle, Chiaverini, Christine, Hubiche, Thomas, Mazereeuw-Hautier, Juliette, Deny, Olivier, Declerck, Dominique, Kémoun, Philippe
المصدر: Quintessence International; Jan2023, Vol. 54 Issue 1, p34-43, 10p
مصطلحات موضوعية: RESEARCH, ERYTHEMA, ANKYLOGLOSSIA, ORAL health, HEALTH status indicators, WORLD health, HEALTH literacy, COMPARATIVE studies, BLISTERS, QUESTIONNAIRES, DESCRIPTIVE statistics, EPIDERMOLYSIS bullosa, ORAL mucosa, PALATE, GINGIVA
مستخلص: Objective: Epidermolysis bullosa (EB) is a rare genetic mucocutaneous disorder characterized by epithelial fragility leading to blister formation on skin and mucous membranes with even minor mechanical trauma. Most EB oral health publications give fragmented information, focusing on only one oral health aspect or one EB type. The aim of this study was to expand the knowledge of the overall oral health status of individuals with dystrophic, junctional, and simplex EB. Method and materials: A comparative multicenter study, including a control group, and based on questionnaires and clinical examinations, was undertaken in three EB expert centers. Results: Most EB (90.2%) participants brushed their teeth at least once a day despite the pain. The prevalence of enamel defects and caries experience did not differ between the 42 EB participants and the 42 age-/sex-matched healthy controls. Gingival inflammation unrelated to dental plaque accumulation was found in EB participants. Blisters, erythema, and erosion/ulceration mainly involved gingiva, buccal mucosa, lips, and palate, with different topographic patterns according to EB type. EB patients whatever the age showed a similar lesion distribution. Simplex and dystrophic EB patients under 12 years old displayed higher lesion severity than junctional EB ones. Only dystrophic type exhibited microstomia and ankyloglossia. Conclusion: Oral health status seemed to benefit from a close collaboration between dental practitioner and dermatologist, and from regular dental examination, starting at a young age and with a focus on prevention. The new appreciation of oral health involvement highlighted by this study is essential for EB patients care, regarding comorbidities and quality of life. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00336572
DOI:10.3290/j.qi.b3479975)