التفاصيل البيبلوغرافية
| العنوان: |
Pharmacogenomics perspective for forensic toxicology: A mini review. |
| المؤلفون: |
Battal, Dilek, Yukseloglu, Emel Hulya, Alkas, Fehmi Burak, Firat, Seyhan Sahan |
| المصدر: |
Medicine Science; Dec2022, Vol. 11 Issue 4, p1738-1744, 7p |
| مصطلحات موضوعية: |
FORENSIC toxicology, PHARMACOGENOMICS, PHARMACOKINETICS, DRUG target, PHYSIOLOGICAL effects of xenobiotics, BIOMARKERS |
| مستخلص: |
Pharmacogenetic and Pharmacogenomics are the study of the association between an individual's genotype and their response to xenobiotics Pharmacokinetic and pharmacodynamics variations can appear at the level of drug-metabolizing enzymes, drug transporters, drug targets or other biomarker genes. Pharmacogenomics can, therefore, be relevant in forensic toxicology. This review presents relevant aspects together with some examples from daily routines. Use of pharmacogenomics in forensic toxicology may add to the understanding of drug toxicity due to genetically predisposed impaired drug metabolism and may provide findings which may be back-extrapolated for the benefits of optimization of antemortem drug therapy. [ABSTRACT FROM AUTHOR] |
|
Copyright of Medicine Science is the property of Society of Turaz Bilim and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder