التفاصيل البيبلوغرافية
| العنوان: |
THE INVESTIGATION OF ANTIMICROBIAL ACTIVITY OF SOME EXTRACTS FROM MOMORDICA CHARANTIA BY USING AS SOLVENT EXTRACTION AN IONIC LIQUID. |
| المؤلفون: |
ŞTEFAN, CLAUDIA SIMONA, CHIŢESCU, CARMEN LIDIA, MANOLACHE, NICUŢA, DIACONU, CAMELIA, ELISEI, ALINA MIHAELA, BEZNEA, ADRIAN, VIORICA IANCU, ALINA, GURĂU, GABRIELA, CHIRIAC, ELENA ROXANA, FULGA, IULIU |
| المصدر: |
Farmacia; Jan/Feb2022, Vol. 70 Issue 1, p144-150, 7p |
| مصطلحات موضوعية: |
MOMORDICA charantia, SOLVENT extraction, IONIC liquids, ANTI-infective agents, EXTRACTS |
| Abstract (English): |
The present study aimed to investigate the antimicrobial efficiency of an extract of Momordica charantia obtained by the sonication method, using an ionic liquid of pyrrolidinium hexanoate (PyrrHexa) as solvent extraction. The results were compared with those obtained by sonication for an extract based on ethanol (Et-OH 70°) and an extract based on ethanol: PyrrHexa (1:1) solvents mixture. The antimicrobial efficiency of ethanol and ionic liquid without vegetable mass was investigated. The results showed that PyrrHexa-based samples demonstrate a more significant antimicrobial potential than the common ethanol solvent. Also, the same variation of antimicrobial efficiency of the analysed extracts was observed for all the strains: alcoholic extract < ethanol: PyrrHexa (1:1) mixture extract < PyrrHexa extract. An efficiency 3.3 times higher than Nystatin 100 IU was demonstrated in the case of Candida albicans strain for both PyrrHexa based extract and PyrrHexa solvent without adding vegetal mass. [ABSTRACT FROM AUTHOR] |
| Abstract (Romanian): |
Scopul acestui studiu a fost investigarea eficacităţii antimicrobiene a unui extract de Momordica charantia obţinut prin metoda sonicării, folosind ca solvent de extracţie un lichid ionic:hexanoat de pirolidiniu (PyrrHexa). Rezultatele au fost comparate cu cele obţinute prin sonicare pentru un extract bazat pe etanol şi un extract pe bază de etanol şi PyrrHexa (1:1). A fost investigată eficienţa antimicrobiană a etanolului şi a lichidului ionic, fără masă vegetală. Rezultatele obţinute arată că eşantioanele pe bază de PyrrHexa prezintă un potenţial antimicrobian mai ridicat decât cel a etanolului. De asemenea, aceeaşi ordine de variaţie a eficienţei antimicrobiene a extractelor analizate a fost observată pentru toate tulpinile microbiene testate: extract alcoolic < extract mixt etanol:PyrrHexa 1:1 < extract pe baza de PyrrHexa. O eficienţă de 3,3 ori mai mare decât Nystatin 100 UI a fost demonstrată în cazul tulpinii Candida albicans pentru extractul pe bază de PyrrHexa si pentru PyrrHexa pur. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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