التفاصيل البيبلوغرافية
| العنوان: |
The Lipidome Fingerprint of Longevity. |
| المؤلفون: |
Jové, Mariona, Mota-Martorell, Natàlia, Pradas, Irene, Galo-Licona, José Daniel, Martín-Gari, Meritxell, Obis, Èlia, Sol, Joaquim, Pamplona, Reinald, Plastina, Pierluigi |
| المصدر: |
Molecules; Sep2020, Vol. 25 Issue 18, p4343, 1p |
| مصطلحات موضوعية: |
LONGEVITY, ANIMAL longevity, COMPARATIVE genetics, ANIMAL species, CELL membranes, FATTY acids |
| مستخلص: |
Lipids were determinants in the appearance and evolution of life. Recent studies disclose the existence of a link between lipids and animal longevity. Findings from both comparative studies and genetics and nutritional interventions in invertebrates, vertebrates, and exceptionally long-lived animal species—humans included—demonstrate that both the cell membrane fatty acid profile and lipidome are a species-specific optimized evolutionary adaptation and traits associated with longevity. All these emerging observations point to lipids as a key target to study the molecular mechanisms underlying differences in longevity and suggest the existence of a lipidome profile of long life. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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