Academic Journal

Necrotizing Hemorrhagic Gastritis following Acute Myeloid Leukemia Induction with Midostaurin: An Unexpected Complication.

التفاصيل البيبلوغرافية
العنوان: Necrotizing Hemorrhagic Gastritis following Acute Myeloid Leukemia Induction with Midostaurin: An Unexpected Complication.
المؤلفون: Shimony, Shai, Reiss Mintz, Hilla, Shvartser Beryozkin, Yulia, Shoham, Avivit, Raanani, Pia, Wolach, Ofir
المصدر: Acta Haematologica; 2020, Vol. 143 Issue 1, p65-68, 4p, 1 Color Photograph
مصطلحات موضوعية: ACUTE myeloid leukemia, GASTRITIS, BLOOD cell count
مستخلص: Midostaurin is a tyrosine multikinase inhibitor approved for the treatment of patients with newly diagnosed acute myeloid leukemia (AML) with mutated Fms-like tyrosine kinase-3. We describe a case report of a 49-year-old AML patient treated with an intensive chemotherapy regimen followed by midostaurin. After achieving complete remission with blood count recovery, he suffered from a serious, rare complication of necrotizing hemorrhagic gastritis with no evidence of infection or malignant infiltration, possibly associated with midostaurin therapy. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00015792
DOI:10.1159/000500975