Academic Journal

The effect of transport on the physiologic stability of neonates with ductal-dependent single-ventricle lesions.

التفاصيل البيبلوغرافية
العنوان: The effect of transport on the physiologic stability of neonates with ductal-dependent single-ventricle lesions.
المؤلفون: Duran, Silvestre R., Aggarwal, Sanjeev, Natarajan, Girija
المصدر: Journal of Maternal-Fetal & Neonatal Medicine; 2/15/2018, Vol. 31 Issue 4, p500-505, 6p
مصطلحات موضوعية: HYPOPLASTIC left heart syndrome, NEONATAL diseases, NEWBORN infants, HEART ventricles, PULMONARY atresia
مستخلص: Objective: To compare the status of infants with hypoplastic left heart syndrome (HLHS) or pulmonary atresia-hypoplastic right heart (PA-HRH) before and following transport using the validated Transport Risk Index of Physiologic Stability (TRIPS) score.Methods: In this retrospective review of infants with HLHS or PA-HRH transported to a Children's Hospital by a pediatric transport team, an increase in TRIPS score (temperature, blood pressure, respiratory status, and response to stimuli) following transport was defined as deterioration. Statistical analyses included t-test (paired and independent), χ2, and McNemar's tests for comparisons between groups with and without deterioration and before and after transport.Results: Our cohort [n = 64; 39 (61%) HLHS and 25 (39%) PA-HRH] was predominantly female (61%), black (56%), and diagnosed antenatally (78%). Median transport time was 20 (10-30) min and age was <12 h in 48 (75%) infants. TRIPS scores worsened after transport in 24 (37.5%) infants, due to temperature (n = 10) or respiratory (n = 7) dysregulation. Infants who deteriorated during transport had HLH more often (83 versus 48%) and lower pH [7.27 (0.12) versus 7.33 (0.07)]. HLH was significantly predictive of deterioration during transport [OR 5.60 (95% C.I. 1.18-26.62)].Conclusions: The physiologic deterioration in a third of infants with single ventricle following short transports is intriguing and may have implications on their optimal place of birth. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:14767058
DOI:10.1080/14767058.2017.1289164