التفاصيل البيبلوغرافية
| العنوان: |
Morvan's syndrome with anti contactin associated protein like 2 - voltage gated potassium channel antibody presenting with syndrome of inappropriate antidiuretic hormone secretion. |
| المؤلفون: |
Sharma, Anjani Kumar, Kaur, Manminder, Paul, Madhuparna |
| المصدر: |
Journal of Neurosciences in Rural Practice; Oct-Dec2016, Vol. 7 Issue 4, p577-580, 4p |
| مصطلحات موضوعية: |
AUTOIMMUNE diseases, PERIPHERAL nervous system, VOLTAGE-gated ion channels, HYPONATREMIA, VASOPRESSIN |
| مستخلص: |
Morvan's syndrome is a rare autoimmune disorder characterized by triad of peripheral nerve hyperexcitability, autonomic dysfunction, and central nervous system symptoms. Antibodies against contactin-associated protein-like 2 (CASPR2), a subtype of voltage-gated potassium channel (VGKC) complex, are found in a significant proportion of patients with Morvan's syndrome and are thought to play a key role in peripheral as well as central clinical manifestations. We report a patient of Morvan's syndrome with positive CASPR2-anti-VGKC antibody having syndrome of inappropriate antidiuretic hormone as a cause of persistent hyponatremia. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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