التفاصيل البيبلوغرافية
| العنوان: |
Alginate-Coated Fe3O4 Hollow Microspheres for Drug Delivery. |
| المؤلفون: |
Li-juan Dong, Gu Jin |
| المصدر: |
Chinese Journal of Chemical Physics (1674-0068); 4/27/2015, Vol. 28 Issue 2, p193-196, 4p |
| مستخلص: |
Novel hollow Fe3O4 nanoparticles for drug delivery were synthesized via a one-step templatefree approach. These nanoparticles were obtained by modifing the Fe3O4 nanoparticles with 3-aminopropyltrimethoxy silane, and then grafting alginate onto the surface of amine magnetic. The hollow structure of Fe3O4 spheres was characterized by TEM, XRD, and XPS. The M-H hysteresis loop indicated that the magnetic spheres exhibit superparamagnetic characteristics at room temperature. Daunorubicin acting as a model drug was loaded into the carrier, and the maximum percent of envelop and load were 28.4% and 14.2% respectively. The drug controlled releasing behaviors of the carriers were compared in di erent pH media. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |