التفاصيل البيبلوغرافية
| العنوان: |
Comparison of conventional ELISA with electrochemiluminescence technology for detection of amyloid-β in plasma. |
| المؤلفون: |
Oh ES, Mielke MM, Rosenberg PB, Jain A, Fedarko NS, Lyketsos CG, Mehta PD, Oh, Esther S, Mielke, Michelle M, Rosenberg, Paul B, Jain, Alka, Fedarko, Neal S, Lyketsos, Constantine G, Mehta, Pankaj D |
| المصدر: |
Journal of Alzheimer's Disease; 2010, Vol. 21 Issue 3, p769-773, 5p |
| مستخلص: |
Plasma amyloid-β (Aβ) level could be useful as a non-invasive biomarker in Alzheimer's disease research. We compared a multiplex electrochemiluminescence detection method with a well established ELISA method for plasma Aβ quantification. Compared to the ELISA method, the electrochemiluminescence detection method demonstrates a statistically significant, but modest correlation. The reasons for this may include the differences in the affinities of antibodies, and purity and source of Aβ peptides used as standards. However, the advantages of electrochemiluminescence detection technology include short processing time and small sample volume. This comparison demonstrates the need for a further study in optimizing this system. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Alzheimer's Disease is the property of IOS Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |