التفاصيل البيبلوغرافية
| العنوان: |
Activation of apoptotic pathway in normal, cancer ovarian cells by epothilone B. |
| المؤلفون: |
Rogalska, Aneta1 zychan@biol.uni.lodz.pl, Szula, Ewa1, Gajek, Arkadiusz1, Marczak, Agnieszka1, Jóźwiak, Zofia1 |
| المصدر: |
Environmental Toxicology & Pharmacology. Sep2013, Vol. 36 Issue 2, p600-610. 11p. |
| مصطلحات موضوعية: |
*OVARIAN cancer treatment, *ANTINEOPLASTIC agents, *APOPTOSIS, *CELLULAR signal transduction, *CANCER cells, *CELL-mediated cytotoxicity |
| مستخلص: |
Highlights: [•] Activation of apoptotic pathway in the ovarian cancer cells by epothilone B. [•] Epo B is 2.6-fold more cytotoxic than PTX. [•] Drug induces programmed cell death mediated by ROS. [•] Release of cytochrome c and mitochondrial membrane depolarization were observed. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |