Academic Journal

Epidermal Growth Factor Contains Both Positive and Negative Determinants for Interaction with ErbB-2/Erb-3 Heterodimers.

التفاصيل البيبلوغرافية
العنوان: Epidermal Growth Factor Contains Both Positive and Negative Determinants for Interaction with ErbB-2/Erb-3 Heterodimers.
المؤلفون: Stortelers, Catelijne, van de Poll, Monique L.M., Lenferink, Anne E.G., Gadellaa, Mireille M., van Zoelen, Claudia, van Zoelen, Everardus J.J.
المصدر: Biochemistry. 4/2/2002, Vol. 41 Issue 13, p4292. 10p. 4 Black and White Photographs, 7 Diagrams, 1 Chart, 10 Graphs.
مصطلحات موضوعية: *DIMERS, *EPIDERMAL growth factor, *DETERMINANTS (Mathematics)
مستخلص: Investigates the presence of positive and negative determinants for interaction with ErbB-2/ErbB-3 heterodimers in epidermal growth factor (EGF). Specificity of EGF-like growth factors for binding to distinct ErbB members; Use of EGF/TGF-α chimeras to examine the requirements for ErbB-2/ErbB-3 activation; Identification of specific residues in the linear N-terminal region.
قاعدة البيانات: Academic Search Index
الوصف
تدمد:00062960
DOI:10.1021/bi012016n