Academic Journal

Cisplatin and gemcitabine in the management of metastatic penile cancer

التفاصيل البيبلوغرافية
العنوان: Cisplatin and gemcitabine in the management of metastatic penile cancer
المؤلفون: Power, Derek G.1 drdgpower@gmail.com, Galvin, David J.2, Cuffe, Sinead1, McVey, Gerald P.3, Mulholland, Paul J.1, Farrelly, Cormac4, Delaney, David W.5, O'Byrne, Kenneth J.1
المصدر: Urologic Oncology. Mar2009, Vol. 27 Issue 2, p187-190. 4p.
مصطلحات موضوعية: *CISPLATIN, *DRUG therapy, *POLYCYCLIC compounds, *BLEOMYCIN
مستخلص: Abstract: Penile cancer is rare and receives little public attention. There are few treatment options for advanced disease. The most active regimen to date is a combination of bleomycin, methotrexate, and cisplatin. However the treatment-related mortality is 11% and hence this combination has not been adapted as a standard of care. We report two cases of advanced penile cancer where a sustained palliative response was observed with combination chemotherapy using cisplatin and gemcitabine. Our experience demonstrates that this is a well tolerated regimen active in this setting. [Copyright &y& Elsevier]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:10781439
DOI:10.1016/j.urolonc.2007.10.015