Academic Journal

Characteristics of lupus erythematosus in dermatology: Analysis of a series of 72 hospital cases in Abidjan, Côte d'Ivoire.

التفاصيل البيبلوغرافية
العنوان: Characteristics of lupus erythematosus in dermatology: Analysis of a series of 72 hospital cases in Abidjan, Côte d'Ivoire.
المؤلفون: Hamdan, Kourouma Sarah1,2, Ange-Sylvain, Allou1,2 alansy06@yahoo.fr, Pacome, Gbandama Koffi1,2, Souleymane, Coulibaly Aziz2, Wilfried, Amani Kaunan2, Isidore, Kouassi Yao1,2, Alexandre, Kouassi Kouamé1,2, Celestin, Ahogo Kouadio1,2, Mamadou, Kaloga1,2, Patrice, Gbery Ildevert1,2, Joseph, Ecra Elidje1,2, Abdoulaye, Sangare1,2
المصدر: Our Dermatology Online / Nasza Dermatologia Online. Jan2025, Vol. 16 Issue 1, p37-42. 6p.
مصطلحات موضوعية: *LUPUS erythematosus, *CLINICAL epidemiology, *UNIVERSITY hospitals, *SEX ratio, *HYDROXYCHLOROQUINE
مصطلحات جغرافية: SUB-Saharan Africa
مستخلص: Background: Several African studies have focused on the clinical features of lupus in black skin, yet the immunological, biological, and imaging profile of the disease remains poorly described in Côte d'Ivoire. Objective: The aim of this study was to investigate the epidemiological, clinical, paraclinical and evolutionary aspects of lupus patients followed at the Dermatology Department of a University Hospital. Methods: This was a cross-sectional, retrospective study of patients received at the dermatology and venereology department of a university hospital over a six-year period. The diagnosis was based on the European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) classification criteria. Results: We included 72 lupus patients. The sex ratio was 9/1 (female-to-male) and the mean age was 37.9 years. Mucocutaneous manifestations were noted in 66% of the patients and were dominated by discoid lupus (88.9%). Rheumatological involvement was the most common extra-dermatological manifestation (21.8%). The main antibodies found were AAN (73.19%), anti-DNAn (45.8%), and anti-Sm Ac (27.8%). The main treatments used were hydroxychloroquine (98%), corticosteroids (37.5%), immunosuppressants (47.2%), and sun protection. Progression was favorable in 37.5%, and 51.2% of the patients were lost to follow-up. Conclusion: Lupus erythematosus is a rare pathology at the dermatology department, with a female predominance. Its main treatment is hydroxychloroquine, and many patients are lost to follow-up. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:20819390
DOI:10.7241/ourd.20251.5