التفاصيل البيبلوغرافية
| العنوان: |
tomoseqr: A Bioconductor package for spatial reconstruction and visualization of 3D gene expression patterns based on RNA tomography. |
| المؤلفون: |
Matsuzawa, Ryosuke1,2 (AUTHOR), Kawahara, Daichi3 (AUTHOR), Kashima, Makoto3,4 (AUTHOR), Hirata, Hiromi3 (AUTHOR), Ozaki, Haruka2 (AUTHOR) haruka.ozaki@md.tsukuba.ac.jp |
| المصدر: |
PLoS ONE. 1/8/2025, Vol. 20 Issue 1, p1-23. 23p. |
| مصطلحات موضوعية: |
*RNA analysis, *GENE expression, *RNA sequencing, *RESEARCH personnel, *PACKAGING design |
| مستخلص: |
RNA tomography computationally reconstructs 3D spatial gene expression patterns genome-widely from 1D tomo-seq data, generated by RNA sequencing of cryosection samples along three orthogonal axes. We developed tomoseqr, an R package designed for RNA tomography analysis of tomo-seq data, to reconstruct and visualize 3D gene expression patterns through user-friendly graphical interfaces. We show the effectiveness of tomoseqr using simulated and real tomo-seq data, validating its utility for researchers. R package tomoseqr is available on Bioconductor (https://doi.org/doi:10.18129/B9.bioc.tomoseqr) and GitHub (https://github.com/bioinfo-tsukuba/tomoseqr). [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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