التفاصيل البيبلوغرافية
| العنوان: |
A reflection-spectroscopy measured skin carotenoid score strongly correlates with plasma concentrations of all major dietary carotenoid species except for lycopene. |
| المؤلفون: |
Wu, Qiang1 (AUTHOR), Cherry, Cheryl Webb1 (AUTHOR), Jilcott Pitts, Stephanie1 (AUTHOR) jilcotts@ecu.edu, Laska, Melissa N.2 (AUTHOR), Craft, Neal3 (AUTHOR), Moran, Nancy E.4 (AUTHOR) |
| المصدر: |
Nutrition Research. Jan2025, Vol. 133, p127-137. 11p. |
| مصطلحات موضوعية: |
*THERAPEUTIC use of antioxidants, *FRUIT, *STATISTICAL correlation, *CROSS-sectional method, *HIGH performance liquid chromatography, *SELF-evaluation, *PEARSON correlation (Statistics), *FOOD consumption, *BODY mass index, *CAROTENOIDS, *QUESTIONNAIRES, *AGE distribution, *DESCRIPTIVE statistics, *RACE, *SPECTRUM analysis, *VEGETABLES, *RESEARCH, *ANTIOXIDANTS, *SKIN tests, *LYCOPENE, *BIOMARKERS, *SENSITIVITY & specificity (Statistics), RESEARCH evaluation |
| مستخلص: |
• Skin carotenoid scores correlate with all plasma carotenoids, except lycopene. • There was no confounding of the relationship by race, age, or body mass index. • Lycopene-rich food intake may not be detected as well as other carotenoids. Skin carotenoids can be measured non-invasively using spectroscopy methods to provide a biomarker of total dietary carotenoid and carotenoid-rich fruit and vegetable intake. However, the degree to which skin carotenoid biomarkers reflect intakes of specific carotenoids must be determined for specific devices. Previously, findings were mixed regarding the correlation between reflection spectroscopy (RS)-assessed skin carotenoids and individual plasma carotenoid concentrations. The current study expands on prior analyses to examine the cross-sectional associations between adult RS-assessed skin carotenoids and individual carotenoid species intakes and plasma concentrations, controlling for potential covariates. We hypothesized that RS-assessed skin carotenoid scores would strongly correlate with all major plasma carotenoid species other than lycopene. Cross-sectional data from 2 prior studies (n = 213 and n = 162) examining the validity and sensitivity of RS-assessed skin carotenoids as a biomarker of fruit and vegetable intake were used. Skin carotenoids were assessed using the Veggie Meter, which quantifies combined skin carotenoid concentrations. Plasma concentrations of α-carotene, β-carotene, β-cryptoxanthin, lycopene, and lutein and zeaxanthin were determined using high-performance liquid chromatography. Self-reported carotenoid intake was estimated from validated food frequency questionnaires. Skin carotenoid scores correlated moderately to strongly with individual plasma carotenoid species (Pearson's r = 0.52 to r = 0.78) except for lycopene (r = 0.04 to r = 0.07). Low correlations between skin carotenoid score and lycopene plasma concentrations and intake could be due to differential deposition, preferential oxidation/degradation, and/or device measurement bias. Validating skin carotenoid measurement techniques relative to other concentration biomarkers informs the interpretation of skin carotenoid biomarkers. Using data from 2 prior studies, we examined correlations between reflection spectroscopy-assessed skin carotenoid scores and individual plasma carotenoids. Skin carotenoid scores were strongly correlated with all individual plasma carotenoids (r = 0.52 to r = 0.78) except for lycopene, where the correlations ranged from r = 0.04 to r = 0.07. Lycopene-rich food intake may not be detected well if using the reflection spectroscopy-device to assess dietary interventions. [Display omitted] [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |