التفاصيل البيبلوغرافية
| العنوان: |
Adult living-donor lobar lung transplant using a small-for-size graft. |
| المؤلفون: |
Nakajima, Daisuke1 (AUTHOR), Sakanoue, Ichiro1 (AUTHOR), Kayawake, Hidenao1 (AUTHOR), Sumitomo, Ryota1 (AUTHOR), Nishikawa, Shigeto1 (AUTHOR), Tanaka, Satona1 (AUTHOR), Yutaka, Yojiro1 (AUTHOR), Menju, Toshi1 (AUTHOR), Date, Hiroshi1 (AUTHOR) |
| المصدر: |
European Journal of Cardio-Thoracic Surgery. Dec2024, Vol. 66 Issue 6, p1-8. 8p. |
| مصطلحات موضوعية: |
*VITAL capacity (Respiration), *LUNG transplantation, *TRANSPLANTATION of organs, tissues, etc., *SURVIVAL rate, *TISSUE viability |
| مستخلص: |
OBJECTIVES This study was designed to examine the outcomes of adult living-donor lobar lung transplants (LDLLTs) using small-for-size grafts. METHODS A calculated graft forced vital capacity of <50% of the predicted forced vital capacity of the recipient was considered to indicate a small-for-size graft. Adult recipients (≥18 years) who underwent LDLLTs between 2008 and 2022 were included in this study. RESULTS We performed 80 adult LDLLTs, using small-for-size grafts in 15 patients and non-small grafts in 65 patients. Grade 3 primary graft dysfunction developed within 72 h after the transplant in 3 patients (20%) in the small group and in 3 patients (4.6%) in the non-small group (P = 0.0763). The 1- and 5-year survival rates were 86.7% and 69.3% in the small group and 93.8% and 77.1% in the non-small group (P = 0.742). In the small group, the native lungs were spared in 8 patients, whereas 2 lobar grafts were implanted with non-spared native lungs in the other 7 patients. The 1- and 5-year survival rates were significantly better in the spared group (both 100%) than in the non-spared group (71.4% and 23.8%; P = 0.0375). The spared group showed a significantly higher median percent forced vital capacity after the transplant than the non-spared group (68.5% vs 44.9%; P = 0.0027). CONCLUSIONS Although the use of small-for-size grafts was associated with a higher rate of severe primary graft dysfunction, no differences were found in survival rates. When the graft is small, the native lung should be partially spared if possible. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |