التفاصيل البيبلوغرافية
| العنوان: |
Low‐dose iron chelation as anti‐oxidative therapy in patients with sickle cell disease: A single‐centre pilot study. |
| المؤلفون: |
Gaartman, Aafke E.1,2 (AUTHOR) a.e.gaartman@amsterdamumc.nl, Beuger, Boukje M.2 (AUTHOR), Ligt, Lydian A.1,2,3 (AUTHOR), Veldthuis, Martijn4 (AUTHOR), Matlung, Hanke L.2,4 (AUTHOR), Meijers, Joost C. M.2,5 (AUTHOR), Schalkwijk, Casper G.6 (AUTHOR), Heer, Koen1,7 (AUTHOR), Heijmans, Jarom1 (AUTHOR), Zwieten, Rob4 (AUTHOR), Biemond, Bart J.1 (AUTHOR), Bruggen, Robin2 (AUTHOR), Nur, Erfan1,2 (AUTHOR) |
| المصدر: |
British Journal of Haematology. Dec2024, p1. 4p. 1 Illustration. |
| مصطلحات موضوعية: |
*SICKLE cell anemia, *INFORMED consent (Medical law), *ERYTHROCYTES, *ERYTHROCYTE membranes, *IRON chelates |
| مستخلص: |
The article discusses a pilot study on the use of low-dose iron chelation as anti-oxidative therapy in patients with sickle cell disease. The study aimed to investigate the potential of iron chelation in reducing oxidative stress and improving various health markers in patients with sickle cell disease. The results showed a decrease in haemolysis markers after treatment, but no significant changes in erythrocyte sickling or adhesion. The study suggests that further research with a larger sample size and longer treatment duration is needed to determine the effectiveness of low-dose iron chelation in managing sickle cell disease. [Extracted from the article] |
| قاعدة البيانات: |
Academic Search Index |