التفاصيل البيبلوغرافية
| العنوان: |
Endolymphatic duct blockage surgery vs. intratympanic steroids for treatment of refractory Ménière's disease. |
| المؤلفون: |
Saliba, Issam1,2 (AUTHOR) issam.saliba@umontreal.ca, Dufour-Fournier, Catherine1,2 (AUTHOR), Asmar, Marc-Henri1 (AUTHOR) |
| المصدر: |
European Archives of Oto-Rhino-Laryngology. Oct2024, Vol. 281 Issue 10, p5159-5167. 9p. |
| مصطلحات موضوعية: |
*MENIERE'S disease, *BONE conduction, *SPEECH perception, *HEARING levels, *VERTIGO, *TINNITUS |
| مستخلص: |
Purpose: To compare the effectiveness of the Endolymphatic duct blockage (EDB) and intratympanic methylprednisolone(ITMP) injection to control refractory Ménière's disease(MD) symptoms and evaluate their impact on hearing level. Study design: Retrospective study in a tertiary care center. Methods: 36 received ITMP injection and 52 EDB. Mean outcome measures at 24 months included vertigo control, tinnitus, aural fullness and hearing level: pure-tone average (PTA), bone conduction average(BCA) and speech discrimination score(SDS). Results: At 24 months postoperatively, 90.4% of the EDB group had complete control of vertigo and 43.4% of the ITMP group (p = 0.001). There was no significant difference in tinnitus or aural fullness control (p = 0.34 and p 0.21 respectively). In each group, the drop in tinnitus and aural fullness frequency at 24 months were significant for EDB (p = 0.03; p < 0.001 respectively) and for ITMP group in tinnitus (p = 0.03) but not aural fullness (p = 0.063). At 24 months, PTA, BCA and SDS were significantly worst in the ITMP group when compared to preoperative levels (p = 0.038, p = 0.027, p = 0.016). PTA in the EDB group was stable with no difference compared to ITMP group (p = 0.48). BCA and SDS in the EDB group were stable and better than the ITMP group (p = 0.032; p = 0.036). In each group, vestibular paresis was not significantly different before (p = 0.06) and after treatment (p = 0.68). Conclusion: EDB is more effective than the ITMP for controlling the vertigo symptoms of Ménière's disease and in preserving hearing function. It is a novel surgical technique with promising results for a complete treatment of Ménière's disease. ITMP decreases the frequency and the severity of the symptoms but only control vertigo in 27.8% of cases. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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