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Background: Left atrium is not a simple passive transport chamber which transfers blood from the pulmonary circulation to the left ventricle. Left atrium has conduit, reservoir and pump functions and multiple variables have been developed to evaluate those functions. Aim of the study: It is comparison of LAFI to traditional echo parameters of Left atrium function in atrial fibrillation and diastolic dysfunction. Methods: This Prospective cross sectional study was conducted among the patients attending the Cardiology OPD with Atrial fibrillation and Diastolic dysfunction in Tertiary care centre, Chennai .The study was done for a period from Jan 2022 to Jan 2023.The study participants fulfilling the inclusion and the exclusion criteria were included in the study throughout the study period. The final attained sample is 75. After obtaining the Institutional Ethical Committee clearance, the study was started after obtaining patients informed consent. Baseline details of study participants like name, age, sex, residence. Anthropometric measurement like height and weight will be taken.Body mass index will be calculated. Echocardiography investigation will be done. After collecting the data it was entered in MS Excel Windows 10.Statistical analysis was done in SPSS 23..P value of <0.005 is considered to be statistically significant. Results: Age, sex, height, weight,Body mass index and Body surface are was found to be not statistically significant between the groups. There is a very weak correlation between LAVI & LAFI in atrial fibrillation group (r= 0.2). There is a strong correlation between A cm/s and LAFI, There is a strong correlation between AVTI and LAFI (r= 0.89). when LAFI <24.5 is set as cut off value, LAFI as a parameter to diagnose left atrial dysfunction has 100% sensitivity, 56%specificity, 53% positive predictive value, 100% negative predictive value. Conclusion: LAFI is low in chronic AF and Diastolic Dysfunction patients in our study. LAFI has high sensitivity and negative predictive value. LAFI is a rhythm independent Left atrium function marker. Thereby we conclude that LAFI is a comprehensive marker of left atrial structural and functional assessment. [ABSTRACT FROM AUTHOR] |
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