التفاصيل البيبلوغرافية
| العنوان: |
COMBINED PH-IMPEDANCE MONITORING - A NECESSARRY TOOL FOR THE GASTROINTESTINAL FUNCTIONAL UNIT. |
| المؤلفون: |
Barboi, Oana-Bogdana1,2, Petrea, Oana-Cristina1,2, Vulpoi, Radu-Alexandru1, Iov, Diana-Elena1,2, Trifan, Anca1,2, Drug, Vasile-Liviu1,2 |
| المصدر: |
Journal of Gastrointestinal & Liver Diseases. 2023 Supplement, Vol. 32, p61-62. 2p. |
| مصطلحات موضوعية: |
*HEARTBURN, *CHEST pain, *CHRONIC cough, *PROTON pump inhibitors, *GASTROESOPHAGEAL reflux, *ASTHMA, *ALIMENTARY canal |
| مصطلحات جغرافية: |
LYON (France) |
| مستخلص: |
Introduction. Multichannel intraluminal esophageal impedance combined to pH-metry (pH-MII) is a sensitive tool for evaluating gastroesophageal reflux disease (GERD). The impedance-pH monitoring diagnostic test determines the frequency of reflux episodes (both acid or nonacid and liquid, gas or mixed) and the time relationship of reflux episodes and symptoms. Extradigestive manifestations and refractory GERD are two of the main recommendations for the assessment of upper digestive tract by pH-MII. Material and method. We conducted a prospective study between January 2022 - March 2023 at our tertiary referral center in North-Eastern Romania that included 26 patients suspected of GERD. All patients were investigated through pHMII. We used a ZepHr® system from Sandhill Scientific and single-use catheters with one pH electrode and 6 impedance electrodes. Patients who underwent MII-pH testing for refractory GERD were tested on proton pump inhibitor (PPI), while patients with no previous evidence of GERD were assessed off PPI. The diagnosis of GERD and phenotypes were based on Lyon metrics. Results. Out of the 26 patients, 14 (53.8%) were male and 12 (46.2%) female, with a mean age of 48.6±13.5 years. Nineteen patients (73.07%) presented with extradigestive GERD symptoms, of whom 7 patients (36.8%) with chronic cough, 7 patients (36.8%) with chronic laryngitis, 4 patients (21.05%) with non-cardiac chest pain and 1 patient (5.26%) with bronchial asthma. The rest of 7 (26.92%) patients were investigated for refractory GERD. After the final analysis of pH-MII tracks, we found GERD in 10 (38.5%) patients, functional heartburn in 6 (23.1%) patients and hypersensitive esophagus in 3 (15.4%) patients. All the 10 patients diagnosed with GERD had acid reflux, with a mean DeMeester Score of 46.7±83.8 and a mean AET of 12.8±20.9%. The mean total number of GERD episodes was 100.3±7.5 and the mean longest reflux episode was of 53.7±85.7 minutes. Conclusion. Multichannel intraluminal esophageal impedance combined to pH-metry represents an important instrument for assessing extradigestive GERD and refractory GERD. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
Full Text Finder