التفاصيل البيبلوغرافية
| العنوان: |
Correlation analysis between urinary cadmium and Hashimoto's Thyroiditis: a cross-sectional study based on NHANES. |
| المؤلفون: |
YAN Shao-shuai1, YU Xu-dong1, DING Zhi-guo1, HU Rui1, LI Lu1, LIU Xiao-he1, SHANG Jian-wei1 sjw3124@163.com |
| المصدر: |
Modern Preventive Medicine. 2023, Vol. 50 Issue 20, p3812-3817. 6p. |
| مصطلحات موضوعية: |
*AUTOIMMUNE thyroiditis, *CADMIUM, *MIDDLE-aged women, *OLDER women, *STATISTICAL correlation, *HEALTH & Nutrition Examination Survey, *CROSS-sectional method |
| مستخلص: |
Objective To explore the potential relationship between urinary cadmium and Hashimoto' s Thyroiditis (HT), and to provide a basis for the prevention and control of HT. Methods Based on the 2007-2012 NHANES database, 4 754 cases with both urinary cadmium concentration indicators and thyroid peroxidase antibody (TPOAb) or thyroglobulin antibody (TgAb) data were included. A logistic regression model was used to explore the association between urinary cadmium and Hashimoto's thyroiditis. And then subgroup analyses were performed for age and sex. Results Urinary cadmium concentrations were significantly higher in people with HT (0. 27 µg/L) than in normal people (0. 24 µg/L) and the difference was statistically significant (Z =5. 542, P <0. 001). Furthermore, after correcting for confounders, the risk of developing HT increased by 13. 4% for each quartile of urinary cadmium (OR = 1. 134, 95% CI: 1. 009-1. 274), and the risk of developing HT increased progressively with the quartile of urinary cadmium (P[rend = 0. 032). Conclusion Cadmium may be a risk factor for HT, and this association may be more pronounced in women and middle-aged and elderly populations. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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