التفاصيل البيبلوغرافية
| العنوان: |
مقایسه تاثیر میدازولام و دکسمدتومیدین بر سطح آرام بخشی ، همودینامیک و عوارض درعمل جراحی استریوتاکسی |
| Alternate Title: |
Effects of Midazolam and Dexmedetomidine on Sedation Levels, Hemodynamics and, Complications under Brain Stereotaxic Surgery. |
| المؤلفون: |
مهرداد مسعودی فر1, بهزاد ناظم رعایا1 behzad_nazem@med.mui.ac.ir, زهرا رحیمی1, مهدی خادمی2 |
| المصدر: |
Jundishapur Scientific Medical Journal. Sep/Oct2019, Vol. 18 Issue 3, p92-100. 9p. |
| مستخلص: |
Background and Objective: Sedation in critical surgeries such as brain stereotaxic surgeries is an important issue due to the need for hemodynamic stability of the patients. Midazolam anddexmedetomidine account as important sedative drugs in clinic. Their role as sedatives are well proven in different studies but there no previous study has attempted to compare their influence on hemodynamic and post operation complication in brain stereotaxic surgery. Subjects and Methods: In this clinical trial, 64 patients candidate for brain stereotaxic surgery went under sedation with midazolam or dexmedetomidine and hemodynamic values such as systolic and diastolic blood pressure, heart rate, respiratory rate, sedation level, patient and surgeon satisfaction, recovery time after surgery and post operation complications were evaluated and collected and data were analyzed. Results: In both groups (midazolam or dexmedetomidine) mean systolic and diastolic blood pressure and heart rate had no differences but respiratory rate in midazolam group was lower than dexmedetomidine group and they also experienced more frequent apnea episodes and decreased O2 saturation. Conclusion: Dexmedetomidine is safer drug in comparison to midazolam and use of this drug is suggested in critical surgeries such as brain stereotaxic surgeries in which hemodynamic stabilities are important. Dexmedetomidine causes fewer respiratory complications than midazolam. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |