Academic Journal
Long-term longitudinal evaluation of the prevalence of SARS-CoV-2 antibodies in healthcare and university workers.
| العنوان: | Long-term longitudinal evaluation of the prevalence of SARS-CoV-2 antibodies in healthcare and university workers. |
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| المؤلفون: | HUYNEN, Pascale, GREGOIRE, Céline, GOFFLOT, Stéphanie, SEIDEL, Laurence, MAES, Nathalie, VRANKEN, Laura, DELCOUR, Sandra, MOUTSCHEN, Michel, HAYETTE, Marie-Pierre, KOLH, Philippe, MELIN, Pierrette, BEGUIN, Yves |
| المصدر: | Scientific Reports, 12 (1), 5156 (2022-03-25) |
| بيانات النشر: | Nature Research, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Delivery of Health Care, Humans, Prevalence, Universities, COVID-19/epidemiology, SARS-CoV-2, Multidisciplinary, Serology, Human health sciences, Immunology & infectious disease, Public health, health care sciences & services, Sciences de la santé humaine, Immunologie & maladie infectieuse, Santé publique, services médicaux & soins de santé |
| الوصف: | Asymptomatic and pauci-symptomatic cases contribute to underestimating the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Moreover, we have few studies available on the longitudinal follow-up of SARS-CoV-2 antibodies after natural infection. We tested staff members of a Belgian tertiary academic hospital for SARS-CoV-2 IgG, IgM, and IgA antibodies. We analyzed the evolution of IgM and IgG after 6 weeks, and the persistence of IgG after 3 and 10 months. At the first evaluation, 409/3776 (10.8%) participants had a positive SARS-CoV-2 serology. Among initially seropositive participants who completed phases 2 and 3, IgM were still detected after 6 weeks in 53.1% and IgG persisted at 12 weeks in 82.0% (97.5% of those with more than borderline titers). IgG levels were higher and increased over time in symptomatic but were lower and stable in asymptomatic participants. After 10 months, 88.5% of participants had sustained IgG levels (97.0% of those with more than borderline titers). |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501 article peer reviewed |
| اللغة: | English |
| Relation: | https://www.nature.com/articles/s41598-022-09215-8.pdf; urn:issn:2045-2322 |
| DOI: | 10.1038/s41598-022-09215-8 |
| URL الوصول: | https://orbi.uliege.be/handle/2268/290559 |
| Rights: | open access http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsorb.290559 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1038/s41598-022-09215-8 |
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