Electronic Resource
The influence of dietary white button mushrooms (Agaricus bisporus) on the kinetics of changes in the proportion of peripheral blood CD4+ CD8+ T lymphocytes in lambs
| العنوان: | The influence of dietary white button mushrooms (Agaricus bisporus) on the kinetics of changes in the proportion of peripheral blood CD4+ CD8+ T lymphocytes in lambs |
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| Additional Titles: | Utjecaj hrane s dodatkom plemenite pečurke (Agaricus bisporus) na kinetiku promjena udjela CD4+ CD8+ T-limfocita u perifernoj krvi janjadi |
| المؤلفون: | Špoljarić, Branimira, Shek Vugrovečki, Ana, Mihelić, Damir, Žura Žaja, Ivona, Vince, Silvijo, Špoljarić, Daniel, Živković, Mario, Kardum Paro, Marijana Mirjana, Vlahović, Ksenija, Samardžija, Marko, Vijtiuk, Nada, Popović, Maja |
| المصدر: | Veterinarski arhiv; ISSN 0372-5480 (Print); ISSN 1331-8055 (Online); Volume 93; Issue 4 |
| بيانات النشر: | University of Zagreb Faculty of Veterinary Medicine 2023 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | The primary focus of the current study was to determine the potential benefits of supplementing sheep diet with white button mushrooms (WBM) in terms of growth, health and the kinetics of systemic CD4+ CD8+ memory T lymphocytes in lambs. Forty-five female lambs (Lika breed) were divided into three groups: A – the control group fed on a free-range pasture for the 222 days of the experiment, while groups B and C were housed in a separate facility for 42 days and fed either a commercial feed mixture (FM) or a FM supplemented with 15% of freshly prepared WBM, respectively, and ad libitum forage. For the remaining 180 days of the experiment, both groups (B and C) of lambs were kept free-range and fed pasture only. The lambs were monitored daily starting on Day 0 (or 90 days of age) before the treatments, weighed and blood sampled on Days 0, 21, 42 and 222, and were clinically observed for the incidence/severity of diarrhea and/or other signs of disease. In addition to morbidity, mortality was also monitored, and dead lambs were examined for gross pathology changes. The lambs fed FM supplemented with WBM (group C) had significantly higher body weight gain (P<0.05) on Days 42 and 222. They were neither diarrheic nor had any mortality cases throughout the experiment. Also, these lambs had a significantly increased (P<0.05) proportion of CD4+CD8+ T cells on Days 42 and 222. The data obtained supported our assumption of the efficacy of dietary WBM in the immunostimulation of CD4+CD8+ memory T lymphocytes in lambs, resulting in protection against on-farm diarrhea and providing an increased growth rate. Primarno usmjerenje ovog istraživanja bilo je utvrditi potencijalne pogodnosti dodavanja plemenite pečurke (PP) u hranu za ovce na rast, zdravlje i kinetiku sistemskih CD4+ CD8+ memorijskih T-limfocita u janjadi. Ukupno 45 janjadi ženskoga spola, pasmine lička pramenka, podijeljeno je u tri skupine. Kontrolna skupina A hranjena je na slobodnoj paši tijekom 222 dana pokusa, dok su skupine B i C bile smještene odvojeno u nastambi tijekom 42 dana i hranjene bilo komercijalnom krmnom smjesom (KS) bilo KS-om s dodatkom 15% svježe pripremljenog PP-a, uz dodatak voluminozne krme ad libitum. Preostalih 180 dana pokusa obje su skupine (B i C) janjadi držane u slobodnom uzgoju i hranjene samo ispašom. Janjad je svakodnevno nadzirana, počevši od nultog dana (ili 90. dana starosti) prije tretmana, vagana je te su uzimani i uzorci krvi 0., 21., 42. i 222. dan. Kliničkim pregledima ustanovljavana je pojavnost/jačina proljeva odnosno drugih znakova bolesti. Osim morbiditeta, praćen je i mortalitet, a uginula je janjad bila pregledana na patoanatomske i histopatološke promjene. Janjad hranjena KS-om s dodatkom PP-a (skupina C) imala je znakovito veći prirast tjelesne mase (P<0,05) 42. i 222. dan. Nije imala proljeva niti su zabilježeni slučajevi uginuća tijekom pokusa. Također, ta je janjad imala znakovito povećan (P<0,05) udio CD4+CD8+ T-stanica 42. i 222. dan pokusa. Dobiveni podaci potvrđuju našu pretpostavku o učinkovitosti PP-a kao dodatka hrani u imunostimulaciji CD4+CD8+ memorijskih T-limfocita u janjadi. Navedeno je rezultiralo zaštitom janjadi od proljeva i njihovim bržim rastom u farmskim uvjetima. |
| مصطلحات الفهرس: | immunostimulation; double-positive T cells; growth; diarrhea; sheep, imunostimulacija; dvostruko pozitivni T-limfociti; rast; proljev; ovca, text, info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion |
| URL: | info:eu-repo/semantics/altIdentifier/doi/10.24099/vet.arhiv.1797 |
| الاتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess Full-text papers can be used for personal or educational purposes only. Authors' and publisher's copyrights must be acknowledged. |
| ملاحظة: | application/pdf English |
| Other Numbers: | HRCAK oai:hrcak.srce.hr:308826 1410371206 |
| المصدر المساهم: | HRCAK PORTAL ZNANSTVENIH CASOPISA REPUB From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1410371206 |
| قاعدة البيانات: | OAIster |
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