Academic Journal
Spinal signalling of C-fiber mediated pleasant touch in humans
| العنوان: | Spinal signalling of C-fiber mediated pleasant touch in humans |
|---|---|
| المؤلفون: | Andrew G Marshall, Manohar L Sharma, Kate Marley, Hakan Olausson, Francis P McGlone |
| المصدر: | eLife, Vol 8 (2019) |
| بيانات النشر: | eLife Sciences Publications Ltd, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Medicine LCC:Science LCC:Biology (General) |
| مصطلحات موضوعية: | touch, C-tactile, pain, spinothalamic tract, anterolateral cordotomy, Medicine, Science, Biology (General), QH301-705.5 |
| الوصف: | C-tactile afferents form a distinct channel that encodes pleasant tactile stimulation. Prevailing views indicate they project, as with other unmyelinated afferents, in lamina I-spinothalamic pathways. However, we found that spinothalamic ablation in humans, whilst profoundly impairing pain, temperature and itch, had no effect on pleasant touch perception. Only discriminative touch deficits were seen. These findings preclude privileged C-tactile-lamina I-spinothalamic projections and imply integrated hedonic and discriminative spinal processing from the body. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2050-084X |
| Relation: | https://elifesciences.org/articles/51642; https://doaj.org/toc/2050-084X |
| DOI: | 10.7554/eLife.51642 |
| URL الوصول: | https://doaj.org/article/f1b97ae916e84155947f9d73d790f60a |
| رقم الانضمام: | edsdoj.f1b97ae916e84155947f9d73d790f60a |
| قاعدة البيانات: | Directory of Open Access Journals |
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