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microProtein Prediction Program (miP3): A Software for Predicting microProteins and Their Target Transcription Factors

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العنوان: microProtein Prediction Program (miP3): A Software for Predicting microProteins and Their Target Transcription Factors
المؤلفون: Niek de Klein, Enrico Magnani, Michael Banf, Seung Yon Rhee
المصدر: International Journal of Genomics, Vol 2015 (2015)
بيانات النشر: Hindawi Limited, 2015.
سنة النشر: 2015
المجموعة: LCC:Genetics
مصطلحات موضوعية: Genetics, QH426-470
الوصف: An emerging concept in transcriptional regulation is that a class of truncated transcription factors (TFs), called microProteins (miPs), engages in protein-protein interactions with TF complexes and provides feedback controls. A handful of miP examples have been described in the literature but the extent of their prevalence is unclear. Here we present an algorithm that predicts miPs and their target TFs from a sequenced genome. The algorithm is called miP prediction program (miP3), which is implemented in Python. The software will help shed light on the prevalence, biological roles, and evolution of miPs. Moreover, miP3 can be used to predict other types of miP-like proteins that may have evolved from other functional classes such as kinases and receptors. The program is freely available and can be applied to any sequenced genome.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2314-436X
2314-4378
Relation: https://doaj.org/toc/2314-436X; https://doaj.org/toc/2314-4378
DOI: 10.1155/2015/734147
URL الوصول: https://doaj.org/article/bf45e404f95f48dea3a45bd026aaaa10
رقم الانضمام: edsdoj.bf45e404f95f48dea3a45bd026aaaa10
قاعدة البيانات: Directory of Open Access Journals
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