التفاصيل البيبلوغرافية
| العنوان: |
Pain profiling in migraine: a systematic review of Quantitative Sensory Testing (QST), Conditioned Pain Modulation (CPM), and Corneal Confocal Microscopy (CCM) |
| المؤلفون: |
Floor Clarissa van Welie, Albert Dahan, Monique van Velzen, Gisela Marie Terwindt |
| المصدر: |
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-21 (2024) |
| بيانات النشر: |
BMC, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Medicine |
| مصطلحات موضوعية: |
Migraine, Chronic migraine (CM), Episodic migraine (EM), Pain profile, Quantitative Sensory Testing (QST), Conditioned Pain Modulation (CPM), Medicine |
| الوصف: |
Abstract Objective The aim of this systematic review is to identify pain profiling parameters that are reliably different between patients with migraine and healthy controls, using Quantitative Sensory Testing (QST) including Temporal Summation (TS), Conditioned Pain Modulation (CPM), and Corneal Confocal Microscopy (CCM). Methods A comprehensive literature search was conducted (up to 23 May 2024). The quality of the research was assessed using the Newcastle-Ottawa Scale (NOS) for non-randomized studies. Results Twenty-eight studies were included after screening. The QST studies indicate that migraine patients exhibit lower pressure pain thresholds (PPT), particularly in the trigeminal region. A previous meta-analysis reported lower heat pain thresholds (HPT). CPM studies suggest a (mild) inhibitory or absent response in migraine patients, not different from controls. High-frequency and chronic migraine patients may exhibit a facilitatory CPM response. With repeated executions of CPM, migraine patients display a diminishing CPM response, a phenomenon not observed in control subjects. CCM investigations in migraine patients revealed conflicting outcomes, likely as a result of small sample sizes and limited characterization of migraine features. Conclusion Pain profiling migraine patients varies due to sensory modality, applied methods, anatomical sites, and migraine features. Understanding pain profiling offers insights into migraine pathophysiology, requiring careful selection of parameters and differentiation among migraine subtypes. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1129-2377 |
| Relation: |
https://doaj.org/toc/1129-2377 |
| DOI: |
10.1186/s10194-024-01932-x |
| URL الوصول: |
https://doaj.org/article/c84ae54ae9834d5d9c81956d340dd941 |
| رقم الانضمام: |
edsdoj.84ae54ae9834d5d9c81956d340dd941 |
| قاعدة البيانات: |
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