Academic Journal
Hepatocyte-specific contrast-enhanced MRI findings of focal nodular hyperplasia-like nodules in the liver following chemotherapy in pediatric cancer patients
| العنوان: | Hepatocyte-specific contrast-enhanced MRI findings of focal nodular hyperplasia-like nodules in the liver following chemotherapy in pediatric cancer patients |
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| المؤلفون: | H. Nursun Özcan, Muşturay Karçaaltıncaba, Turgut Seber, Bilgehan Yalçın, Berna Oğuz, Canan Akyüz, Mithat Haliloğlu |
| المصدر: | Diagnostic and Interventional Radiology, Vol 26, Iss 4, Pp 370-376 (2020) |
| بيانات النشر: | Galenos Publishing House, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine |
| مصطلحات موضوعية: | Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| الوصف: | PURPOSEWe aimed to assess the MRI findings and follow-up of multiple focal nodular hyperplasia (FNH)- like lesions in pediatric cancer patients diagnosed by imaging findings.METHODSWe retrospectively analyzed clinical data and MRI examinations of 16 pediatric patients, who had been scanned using gadoxetate disodium (n=13) and gadobenate dimeglumine (n=3). Hepatic nodules were reviewed according to their number, size, contour, T1- and T2-weighted signal intensities, arterial, portal, delayed and hepatobiliary phase enhancement patterns. Follow-up images were evaluated for nodule size, number, and appearance.RESULTSAll 16 patients received chemotherapy in due course. Time interval between the initial diagnosis of cancer and detection of the hepatic nodule was 2–14 years. Three patients had a single lesion, 13 patients had multiple nodules. The median size of the largest nodules was 19.5 mm (range, 8–41 mm). Among 16 patients that received hepatocyte-specific agents, FNH-like nodules appeared hyperintense in 11 and isointense in 5 on the hepatobiliary phase. During follow-up, increased number and size of the nodules were seen in 4 patients. The nodules showed growth between 6–15 mm.CONCLUSIONLiver MRI using hepatocyte-specific agents is a significant imaging method for the diagnosis of FNH-like lesions, which can occur in a variety of diseases. Lesions can increase in size and number in pediatric patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1305-3825 1305-3612 |
| Relation: | http://www.dirjournal.org/archives/archive-detail/article-preview/hepatocyte-specific-contrast-enhanced-mr-findings-/54736; https://doaj.org/toc/1305-3825; https://doaj.org/toc/1305-3612 |
| DOI: | 10.5152/dir.2019.19398 |
| URL الوصول: | https://doaj.org/article/7e508dfb5f674fbf9e4d7d0e3ff9205a |
| رقم الانضمام: | edsdoj.7e508dfb5f674fbf9e4d7d0e3ff9205a |
| قاعدة البيانات: | Directory of Open Access Journals |
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