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Role of Cervical Cerclage and Vaginal Progesterone in the Treatment of Cervical Incompetence with/without Preterm Birth History

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العنوان: Role of Cervical Cerclage and Vaginal Progesterone in the Treatment of Cervical Incompetence with/without Preterm Birth History
المؤلفون: Shao-Wei Wang, Lin-Lin Ma, Shuai Huang, Lin Liang, Jun-Rong Zhang
المصدر: Chinese Medical Journal, Vol 129, Iss 22, Pp 2670-2675 (2016)
بيانات النشر: Wolters Kluwer, 2016.
سنة النشر: 2016
المجموعة: LCC:Medicine
مصطلحات موضوعية: Cervical Cerclage, Cervical Incompetence, Preterm Delivery, Vaginal Progesterone, Medicine
الوصف: Background: Preterm birth (PTB) is the leading cause of perinatal morbidity and mortality worldwide, and its prevention is an important health-care priority. The cervical incompetence is a well-known risk factor for PTB and its incidence is about 0.1–2.0%, while there is no ideal optimum treatment recommended currently. The cervical incompetence causes about 15% of habitual abortion in 16–28 weeks. This study aimed to evaluate the effectiveness and safety of cervical cerclage and vaginal progesterone in the treatment of cervical incompetence with/without PTB history. Methods: We retrospectively observed the pregnancy outcome of 198 patients diagnosed with cervical incompetence from January 2010 to October 2015 in Beijing Hospital. Among the 198 women involved, women who had at least one PTB before 32 weeks (including abortion in the second trimester attributed to the cervical competence) were assigned to the PTB history cohort, and others were assigned to the non-PTB history cohort. All women underwent cerclage placement (cervical cerclage group) or administrated with vaginal progesterone (vaginal progesterone group) until delivery. The outcomes of interest were the differences in gestational age at delivery, the rate of premature delivery, neonatal outcome, complications, and route of delivery between the two treatment groups. Results: Among the 198 patients with cervical incompetence, 116 patients in PTB history cohort and 80 patients in non-PTB history cohort were included in the final analysis. In the PTB history cohort, cervical cerclage group had significantly longer cervical length at 2 weeks after the start of treatment (23.1 ± 4.6 mm vs. 12.4 ± 9.1 mm, P = 0.002), higher proportion of delivery ≥37 weeks' gestation (63.4% vs. 33.3%, P = 0.008), bigger median birth weight (2860 g vs. 2250 g, P = 0.031), and lower proportion of neonates whose 1-min Apgar score
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0366-6999
Relation: http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=22;spage=2670;epage=2675;aulast=Wang; https://doaj.org/toc/0366-6999
DOI: 10.4103/0366-6999.193451
URL الوصول: https://doaj.org/article/67dc3ee3b0874f059a59695291ddb165
رقم الانضمام: edsdoj.67dc3ee3b0874f059a59695291ddb165
قاعدة البيانات: Directory of Open Access Journals
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