Academic Journal

Usefulness of fluorodeoxyglucose positron emission tomography/computed tomography for detection of a neuroblastic nodule in a ganglioneuroblastoma: a case report

التفاصيل البيبلوغرافية
العنوان: Usefulness of fluorodeoxyglucose positron emission tomography/computed tomography for detection of a neuroblastic nodule in a ganglioneuroblastoma: a case report
المؤلفون: Yuka Takeda, Hideki Sano, Asuka Kawano, Kazuhiro Mochizuki, Nobuhisa Takahashi, Shogo Kobayashi, Yoshihiro Ohara, Kazuhiro Tasaki, Mitusuaki Hosoya, Atsushi Kikuta
المصدر: Journal of Medical Case Reports, Vol 12, Iss 1, Pp 1-5 (2018)
بيانات النشر: BMC, 2018.
سنة النشر: 2018
المجموعة: LCC:Medicine
مصطلحات موضوعية: FDG PET/CT, Ganglioneuroblastoma, nodular, Ganglioneuroma, Neuroblastoma, Medicine
الوصف: Abstract Background Ganglioneuroblastoma, nodular is defined as a composite tumor of biologically distinct clones. The peripheral neuroblastic tumors in this category are characterized by the presence of grossly visible neuroblastoma nodules coexisting with ganglioneuroblastoma, intermixed, or with ganglioneuroma. Making a correct diagnosis of ganglioneuroblastoma, nodular is often difficult by biopsy or partial tumor resection, because the neuroblastic nodule could be hidden and not sampled for pathological examination. Case presentation We report a case of a Japanese boy aged 3 years, 8 months, with an unresectable abdominal tumor and elevated vanillylmandelic acid and homovanillic acid levels. The initial biopsy was ganglioneuroma. However, after the second biopsy from a hidden neuroblastoma nodule that was clearly highlighted by fluorodeoxyglucose positron emission tomography/computed tomography, we reached the diagnosis of ganglioneuroblastoma, nodular. Because the nodule demonstrated neuroblastoma, differentiating subtype, with a low mitosis-karyorrhexis index (favorable histology) and nonamplified MYCN, the boy was treated according to the intermediate-risk protocol and is now alive and well 4 years after the diagnosis. Conclusions This case illustrates the critical role of fluorodeoxyglucose positron emission tomography/computed tomography for detecting a neuroblastoma nodule in a ganglioneuroblastoma.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1752-1947
Relation: http://link.springer.com/article/10.1186/s13256-018-1640-0; https://doaj.org/toc/1752-1947
DOI: 10.1186/s13256-018-1640-0
URL الوصول: https://doaj.org/article/476a47351a074e6889e1f43519fbaacf
رقم الانضمام: edsdoj.476a47351a074e6889e1f43519fbaacf
قاعدة البيانات: Directory of Open Access Journals