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Parathyroid carcinoma arising from auto-transplanted parathyroid tissue after Total Parathyroidectomy in chronic kidney disease patient: a case report

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العنوان: Parathyroid carcinoma arising from auto-transplanted parathyroid tissue after Total Parathyroidectomy in chronic kidney disease patient: a case report
المؤلفون: Ho-Ryun Won, Jae Yoon Kang, In Ho Lee, Jin-Man Kim, Jae Won Chang, Bon Seok Koo
المصدر: BMC Nephrology, Vol 20, Iss 1, Pp 1-6 (2019)
بيانات النشر: BMC, 2019.
سنة النشر: 2019
المجموعة: LCC:Diseases of the genitourinary system. Urology
مصطلحات موضوعية: Parathyroid carcinoma, Chronic kidney disease, Secondary hyperparathyroidism, Parathyroidectomy, Auto-transplantation, Diseases of the genitourinary system. Urology, RC870-923
الوصف: Abstract Background Secondary hyperparathyroidism is a common complication in patients with chronic kidney disease that requires vigilant treatment due to its high mortality rate. Pharmacologic therapy is recommended as an initial treatment; if there is no response, a total parathyroidectomy is performed. In some cases, surgery is accompanied by auto-transplantation of parathyroid tissue. Case presentation The patient was diagnosed with chronic kidney disease and received a kidney transplant. However, due to rejection of the transplanted kidney, medical nephrectomy was carried out and routine hemodialysis was initiated and observed. At this time, secondary hyperparathyroidism with elevated parathyroid hormone and hyperphosphatemia developed and pharmacologic treatment was applied. However, there was no response to pharmacologic treatment; therefore, total parathyroidectomy with auto-transplantation was performed. Eight years after surgery, a growing mass was observed in the transplantation site, accompanied by an elevation of parathyroid hormone. A complete resection of the mass was performed, and the patient was diagnosed with parathyroid carcinoma. Additional adjuvant radiation therapy was ordered, and the patient is being monitored. Conclusions This is a rare but remarkable case of parathyroid carcinoma arising from auto-transplanted parathyroid tissue after total parathyroidectomy in a patient with secondary hyperparathyroidism. We suggest caution should be taken when choosing to auto- transplant parathyroid tissue and that careful postoperative observation should be performed.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2369
Relation: http://link.springer.com/article/10.1186/s12882-019-1606-5; https://doaj.org/toc/1471-2369
DOI: 10.1186/s12882-019-1606-5
URL الوصول: https://doaj.org/article/a30a9ac7d44c4586904a79fe4b32b83d
رقم الانضمام: edsdoj.30a9ac7d44c4586904a79fe4b32b83d
قاعدة البيانات: Directory of Open Access Journals
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