Academic Journal
Physicochemical properties and effect of bioceramic root canal filling for primary teeth on osteoblast biology
| العنوان: | Physicochemical properties and effect of bioceramic root canal filling for primary teeth on osteoblast biology |
|---|---|
| المؤلفون: | Victor Manuel OCHOA RODRÍGUEZ, Mario TANOMARU-FILHO, Elisandra Márcia RODRIGUES, Eduarda de Oliveira BUGANÇA, Juliane Maria GUERREIRO-TANOMARU, Gisele FARIA |
| المصدر: | Journal of Applied Oral Science, Vol 29 (2021) |
| بيانات النشر: | University of São Paulo, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Dentistry |
| مصطلحات موضوعية: | Cytotoxicity, Endodontics, Primary teeth, Root Canal Filling Materials, Dentistry, RK1-715 |
| الوصف: | Abstract Bio-C Pulpecto (Bio-CP) was recently developed as the first bioceramic root filling material for primary teeth. Objective To evaluate the physicochemical properties of radiopacity, setting time, pH, cytocompatibility and potential of Bio-CP to induce mineralisation, compared with (1) Calen thickened with zinc oxide (Calen-ZO), and (2) zinc oxide and eugenol (ZOE). Methodology Physicochemical properties were evaluated according to ISO 6876. Saos-2 (human osteoblast-like cell line) exposed to extracts of the materials were subjected to assays of methyl thiazolyl tetrazolium, neutral red, alkaline phosphatase (ALP) activity and mineralised nodule production. The results were analysed using one-way or two-way ANOVA and Tukey’s or Bonferroni’s post-tests (α=0.05). Results All the materials showed radiopacity higher than 3 mm Al. Bio-CP had lower pH than Calen-ZO, but higher pH than ZOE. Calen-ZO and Bio-CP did not set. The setting time for ZOE was 110 min. The cytocompatibility order was Calen-ZO > Bio-CP > ZOE (1:2, 1:4 dilutions) and Calen-ZO > Bio-CP = ZOE (1:12, 1:24 dilutions) and Calen-ZO = Bio-CP > ZOE (1:32 dilution). Bio-CP induced greater ALP activity at 7 days, and greater mineralised nodule production, compared to Calen-ZO (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-7765 1678-7757 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572021000100422&tlng=en; http://www.scielo.br/pdf/jaos/v29/1678-7757-jaos-29-e20200870.pdf; https://doaj.org/toc/1678-7765 |
| DOI: | 10.1590/1678-7757-2020-0870 |
| URL الوصول: | https://doaj.org/article/263e58e4f7294cf0bb93653e42f3f102 |
| رقم الانضمام: | edsdoj.263e58e4f7294cf0bb93653e42f3f102 |
| قاعدة البيانات: | Directory of Open Access Journals |
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