Academic Journal
Sero-prevalence of yellow fever and related Flavi viruses in Ethiopia: a public health perspective
| العنوان: | Sero-prevalence of yellow fever and related Flavi viruses in Ethiopia: a public health perspective |
|---|---|
| المؤلفون: | Mesfin Mengesha Tsegaye, Berhane Beyene, Workenesh Ayele, Almaz Abebe, Israel Tareke, Amadou Sall, Sergio Yactayo, Messeret E. Shibeshi, Erin Staples, Desalegn Belay, Abrham Lilay, Abebe Alemu, Emana Alemu, Adugna Kume, Alemnesh H/Mariam, Olivier Ronveaux, Mesfin Tefera, Woubayehu Kassa, Abyot Bekele Weyessa, Daddi Jima, Amha Kebede, Adamu Tayachew |
| المصدر: | BMC Public Health, Vol 18, Iss 1, Pp 1-10 (2018) |
| بيانات النشر: | BMC, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Yellow fever, Flaviviruses, Risk assessment, Ethiopia, Public aspects of medicine, RA1-1270 |
| الوصف: | Abstract Background Yellow fever (YF) is a viral hemorrhagic fever, endemic in the tropical forests of Africa and Central and South America. The disease is transmitted by mosquitoes infected with the yellow fever virus (YFV). Ethiopia was affected by the largest YF outbreak since the vaccination era during 1960–1962. The recent YF outbreak occurred in 2013 in Southern part of the country. The current survey of was carried out to determine the YF seroprevalence so as to make recommendations from YF prevention and control in Ethiopia. Methodology A multistage cluster design was utilized. Consequently, the country was divided into 5 ecological zones and two sampling towns were picked per zone randomly. A total of 1643 serum samples were collected from human participants. The serum samples were tested for IgG antibody against YFV using ELISA. Any serum sample testing positive by ELISA was confirmed by plaque reduction neutralization test (PRNT). In addition, differential testing was performed for other flaviviruses, namely dengue, Zika and West Nile viruses. Result Of the total samples tested, 10 (0.61%) were confirmed to be IgG positive against YFV and confirmed with PRNT. Nine (0.5%) samples were antibody positive for dengue virus, 15(0.9%) forWest Nile virus and 7 (0.4%) for Zika virus by PRNT. Three out of the five ecological zones namely zones 1, 3 and 5 showed low levels ( |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1471-2458 |
| Relation: | http://link.springer.com/article/10.1186/s12889-018-5726-9; https://doaj.org/toc/1471-2458 |
| DOI: | 10.1186/s12889-018-5726-9 |
| URL الوصول: | https://doaj.org/article/21047d4f58f2464b873b0bfb167c4244 |
| رقم الانضمام: | edsdoj.21047d4f58f2464b873b0bfb167c4244 |
| قاعدة البيانات: | Directory of Open Access Journals |
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