التفاصيل البيبلوغرافية
| العنوان: |
Comparative efficacy of micro-erythrocyte sedimentation rate (m-ESR) and C-reactive protein (CRP) as a neonatal septic screening marker—a single-center, retrospective observational study |
| المؤلفون: |
Thirunavukkarasu Arun Babu, Arundhathi Shankaralingappa, Vijayasankar Vijayadevagaran, Vijayan Sharmila, Vinoth Kumar Kalidoss |
| المصدر: |
Egyptian Pediatric Association Gazette, Vol 71, Iss 1, Pp 1-5 (2023) |
| بيانات النشر: |
SpringerOpen, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Pediatrics |
| مصطلحات موضوعية: |
C-reactive protein, Micro-ESR, Neonatal sepsis, Screening test, Pediatrics, RJ1-570 |
| الوصف: |
Abstract Background Neonatal sepsis is a clinical syndrome characterized by signs and symptoms of infection with or without accompanying bacteremia in neonatal period. Most of neonatal sepsis-related morbidity and mortality can be prevented by early diagnosis and treatment with appropriate antimicrobial agents. Micro-erythrocyte sedimentation rate (m-ESR) is a simple, inexpensive, and rapid screening test for neonatal sepsis that can be done even in resource limited setups. Objectives To compare the efficacy of m-ESR with C-reactive protein (CRP) as a screening tool in neonatal sepsis. Methodology A retrospective chart-based analysis was done in division of neonatology, of our tertiary care hospital over a period of 21 months. A total of 202 suspected cases of neonatal sepsis with documented CRP and micro-ESR values were included. We evaluated the role of micro-ESR as a screening tool in neonatal sepsis in comparison with CRP. The validity and reliability of micro-ESR in comparison to CRP were estimated and its sensitivity, specificity, positive, and negative predictive value to diagnose sepsis were calculated. Results There was a significant correlation between micro-ESR and CRP with a moderate degree of agreement, especially in ‘late onset sepsis’ group. The overall sensitivity, specificity, positive predictive value and negative predictive value of micro-ESR were 67%, 84%, 58%, and 89% respectively. Conclusion Micro-ESR is a simple, inexpensive test comparable to CRP in screening for neonatal sepsis. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2090-9942 |
| Relation: |
https://doaj.org/toc/2090-9942 |
| DOI: |
10.1186/s43054-023-00178-7 |
| URL الوصول: |
https://doaj.org/article/d1503795154448b6bbcb301077e677ae |
| رقم الانضمام: |
edsdoj.1503795154448b6bbcb301077e677ae |
| قاعدة البيانات: |
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