Academic Journal
A Pathophysiological Role of Plasma Indoxyl Sulfate in Patients with Heart Failure
| العنوان: | A Pathophysiological Role of Plasma Indoxyl Sulfate in Patients with Heart Failure |
|---|---|
| المؤلفون: | Miki Imazu, Hiroyuki Takahama, Kazuhiro Shindo, Takuya Hasegawa, Hideaki Kanzaki, Toshihisa Anzai, Hiroshi Asanuma, Toshisuke Morita, Masanori Asakura, Masafumi Kitakaze |
| المصدر: | International Journal of Gerontology, Vol 11, Iss 2, Pp 62-66 (2017) |
| بيانات النشر: | Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM), 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Geriatrics |
| مصطلحات موضوعية: | AST-120, cardiovascular hemodynamics, heart failure, indoxyl sulfate, Geriatrics, RC952-954.6 |
| الوصف: | Background: One of uremic toxins, indoxyl sulfate (IS), is associated with cardiovascular events. This study aimed to measure the plasma IS levels in patients with and without chronic heart failure (CHF). Methods: We measured plasma IS levels in 49 patients with CHF and an estimated glomerular filtration rate (eGFR) of 40–60 ml/min/1.73 m2 from our institute. These were compared with 31 healthy subjects without CHF (a control), but with comparable eGFR levels, from our resident cohort study. We also test the effect of AST-120 (the oral adsorbent) in 16 CHF patients. Results: The plasma IS levels in 49 CHF patients increased (1.38 ± 0.84 (SD) vs 0.12 ± 0.07 μg/ml (a control), p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1873-9598 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S187395981730145X; https://doaj.org/toc/1873-9598 |
| DOI: | 10.1016/j.ijge.2016.05.010 |
| URL الوصول: | https://doaj.org/article/11fc1453ae514c4e9b1320d33b5ec996 |
| رقم الانضمام: | edsdoj.11fc1453ae514c4e9b1320d33b5ec996 |
| قاعدة البيانات: | Directory of Open Access Journals |
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