Academic Journal
أعرض في EDS

Evaluation of surfactant effect on β-poly(L-malic acid) production by Aureobasidium pullulans

التفاصيل البيبلوغرافية
العنوان: Evaluation of surfactant effect on β-poly(L-malic acid) production by Aureobasidium pullulans
المؤلفون: Haisong Yin, Cui Gao, Kai Ye, Tingbin Zhao, Aiyou Sun, Changsheng Qiao
المصدر: Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 954-966 (2019)
بيانات النشر: Taylor & Francis Group, 2019.
سنة النشر: 2019
المجموعة: LCC:Biotechnology
مصطلحات موضوعية: aureobasidium pullulans, poly (β-l-malic acid), tween 80, mechanism, Biotechnology, TP248.13-248.65
الوصف: β-poly(L-malic acid) (PMLA) is a highly water-soluble biopolymer used in medicine and other industries. PMLA is usually biosynthesized by Aureobasidium pullulans, but in low concentrations, which has restricted its further large-scale production. Here effects of surfactants on PMLA production were investigated. Of various surfactants examined, the addition of Tween 80 at the start of cell growth increased mycelial growth, PMLA production, PMLA productivity and the ratio of PMLA to cell biomass concentration (Yp/x) of A. pullulans. Transmission electron microscopy and flow cytometry showed that cell membrane permeability was increased, improving the secretion of PMLA and uptake of nutrients and oxygen. Proteomic analysis showed that key pathways of PMLA synthesis, along with cellular energy metabolism, were enhanced. Moreover, glutathione (GSH) synthesis and anti-oxidation capacity were also improved. These results indicated that the addition of Tween 80 is an efficient approach for improving the production of PMLA.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1310-2818
1314-3530
13102818
Relation: https://doaj.org/toc/1310-2818; https://doaj.org/toc/1314-3530
DOI: 10.1080/13102818.2019.1631718
URL الوصول: https://doaj.org/article/d03cd36b1b9a488fb5eda9ffc6db7526
رقم الانضمام: edsdoj.03cd36b1b9a488fb5eda9ffc6db7526
قاعدة البيانات: Directory of Open Access Journals
ResultId 1
Header edsdoj
Directory of Open Access Journals
edsdoj.03cd36b1b9a488fb5eda9ffc6db7526
918
3
Academic Journal
academicJournal
917.664306640625
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsdoj&AN=edsdoj.03cd36b1b9a488fb5eda9ffc6db7526&custid=s6537998&authtype=sso
FullText Array ( [Availability] => 0 )
Array ( [0] => Array ( [Url] => https://doaj.org/article/d03cd36b1b9a488fb5eda9ffc6db7526 [Name] => EDS - DOAJ [Category] => fullText [Text] => View record in DOAJ [MouseOverText] => View record in DOAJ ) [1] => Array ( [Url] => https://resolver.ebscohost.com/openurl?custid=s6537998&groupid=main&authtype=ip,guest&sid=EBSCO:edsdoj&genre=article&issn=13102818&ISBN=&volume=33&issue=1&date=20190101&spage=954&pages=954-966&title=Biotechnology & Biotechnological Equipment&atitle=Evaluation%20of%20surfactant%20effect%20on%20%CE%B2-poly%28L-malic%20acid%29%20production%20by%20Aureobasidium%20pullulans&id=DOI:10.1080/13102818.2019.1631718 [Name] => Full Text Finder (s6537998api) [Category] => fullText [Text] => Full Text Finder [Icon] => https://imageserver.ebscohost.com/branding/images/FTF.gif [MouseOverText] => Full Text Finder ) )
Items Array ( [Name] => Title [Label] => Title [Group] => Ti [Data] => Evaluation of surfactant effect on β-poly(L-malic acid) production by Aureobasidium pullulans )
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => <searchLink fieldCode="AR" term="%22Haisong+Yin%22">Haisong Yin</searchLink><br /><searchLink fieldCode="AR" term="%22Cui+Gao%22">Cui Gao</searchLink><br /><searchLink fieldCode="AR" term="%22Kai+Ye%22">Kai Ye</searchLink><br /><searchLink fieldCode="AR" term="%22Tingbin+Zhao%22">Tingbin Zhao</searchLink><br /><searchLink fieldCode="AR" term="%22Aiyou+Sun%22">Aiyou Sun</searchLink><br /><searchLink fieldCode="AR" term="%22Changsheng+Qiao%22">Changsheng Qiao</searchLink> )
Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 954-966 (2019) )
Array ( [Name] => Publisher [Label] => Publisher Information [Group] => PubInfo [Data] => Taylor & Francis Group, 2019. )
Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2019 )
Array ( [Name] => Subset [Label] => Collection [Group] => HoldingsInfo [Data] => LCC:Biotechnology )
Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => <searchLink fieldCode="DE" term="%22aureobasidium+pullulans%22">aureobasidium pullulans</searchLink><br /><searchLink fieldCode="DE" term="%22poly+%28β-l-malic+acid%29%22">poly (β-l-malic acid)</searchLink><br /><searchLink fieldCode="DE" term="%22tween+80%22">tween 80</searchLink><br /><searchLink fieldCode="DE" term="%22mechanism%22">mechanism</searchLink><br /><searchLink fieldCode="DE" term="%22Biotechnology%22">Biotechnology</searchLink><br /><searchLink fieldCode="DE" term="%22TP248%2E13-248%2E65%22">TP248.13-248.65</searchLink> )
Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => β-poly(L-malic acid) (PMLA) is a highly water-soluble biopolymer used in medicine and other industries. PMLA is usually biosynthesized by Aureobasidium pullulans, but in low concentrations, which has restricted its further large-scale production. Here effects of surfactants on PMLA production were investigated. Of various surfactants examined, the addition of Tween 80 at the start of cell growth increased mycelial growth, PMLA production, PMLA productivity and the ratio of PMLA to cell biomass concentration (Yp/x) of A. pullulans. Transmission electron microscopy and flow cytometry showed that cell membrane permeability was increased, improving the secretion of PMLA and uptake of nutrients and oxygen. Proteomic analysis showed that key pathways of PMLA synthesis, along with cellular energy metabolism, were enhanced. Moreover, glutathione (GSH) synthesis and anti-oxidation capacity were also improved. These results indicated that the addition of Tween 80 is an efficient approach for improving the production of PMLA. )
Array ( [Name] => TypeDocument [Label] => Document Type [Group] => TypDoc [Data] => article )
Array ( [Name] => Format [Label] => File Description [Group] => SrcInfo [Data] => electronic resource )
Array ( [Name] => Language [Label] => Language [Group] => Lang [Data] => English )
Array ( [Name] => ISSN [Label] => ISSN [Group] => ISSN [Data] => 1310-2818<br />1314-3530<br />13102818 )
Array ( [Name] => NoteTitleSource [Label] => Relation [Group] => SrcInfo [Data] => https://doaj.org/toc/1310-2818; https://doaj.org/toc/1314-3530 )
Array ( [Name] => DOI [Label] => DOI [Group] => ID [Data] => 10.1080/13102818.2019.1631718 )
Array ( [Name] => URL [Label] => Access URL [Group] => URL [Data] => <link linkTarget="URL" linkTerm="https://doaj.org/article/d03cd36b1b9a488fb5eda9ffc6db7526" linkWindow="_blank">https://doaj.org/article/d03cd36b1b9a488fb5eda9ffc6db7526</link> )
Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsdoj.03cd36b1b9a488fb5eda9ffc6db7526 )
RecordInfo Array ( [BibEntity] => Array ( [Identifiers] => Array ( [0] => Array ( [Type] => doi [Value] => 10.1080/13102818.2019.1631718 ) ) [Languages] => Array ( [0] => Array ( [Text] => English ) ) [PhysicalDescription] => Array ( [Pagination] => Array ( [PageCount] => 13 [StartPage] => 954 ) ) [Subjects] => Array ( [0] => Array ( [SubjectFull] => aureobasidium pullulans [Type] => general ) [1] => Array ( [SubjectFull] => poly (β-l-malic acid) [Type] => general ) [2] => Array ( [SubjectFull] => tween 80 [Type] => general ) [3] => Array ( [SubjectFull] => mechanism [Type] => general ) [4] => Array ( [SubjectFull] => Biotechnology [Type] => general ) [5] => Array ( [SubjectFull] => TP248.13-248.65 [Type] => general ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Evaluation of surfactant effect on β-poly(L-malic acid) production by Aureobasidium pullulans [Type] => main ) ) ) [BibRelationships] => Array ( [HasContributorRelationships] => Array ( [0] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Haisong Yin ) ) ) [1] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Cui Gao ) ) ) [2] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Kai Ye ) ) ) [3] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Tingbin Zhao ) ) ) [4] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Aiyou Sun ) ) ) [5] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Changsheng Qiao ) ) ) ) [IsPartOfRelationships] => Array ( [0] => Array ( [BibEntity] => Array ( [Dates] => Array ( [0] => Array ( [D] => 01 [M] => 01 [Type] => published [Y] => 2019 ) ) [Identifiers] => Array ( [0] => Array ( [Type] => issn-print [Value] => 13102818 ) [1] => Array ( [Type] => issn-print [Value] => 13143530 ) ) [Numbering] => Array ( [0] => Array ( [Type] => volume [Value] => 33 ) [1] => Array ( [Type] => issue [Value] => 1 ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Biotechnology & Biotechnological Equipment [Type] => main ) ) ) ) ) ) )
IllustrationInfo