Academic Journal
Effect of different calcium sulfate aspect ratios and chitosan addition methods on the interface properties of calcium sulfate/chitosan composite bone cement
| العنوان: | Effect of different calcium sulfate aspect ratios and chitosan addition methods on the interface properties of calcium sulfate/chitosan composite bone cement |
|---|---|
| المؤلفون: | Liuyun Jiang, Chunyan Tang, Shuo Tang, Yuqing Wang, Qi Ouyang, Xiang Hu |
| المصدر: | MedComm – Biomaterials and Applications, Vol 3, Iss 4, Pp n/a-n/a (2024) |
| بيانات النشر: | Wiley, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Materials of engineering and construction. Mechanics of materials LCC:Medical technology |
| مصطلحات موضوعية: | biodegradable, calcium sulfate, chitosan, injectable, Materials of engineering and construction. Mechanics of materials, TA401-492, Medical technology, R855-855.5 |
| الوصف: | Abstract It is a great challenge to improve the properties of pure calcium sulfate bone cement. Here, two calcium sulfate hemihydrate powders with different aspect ratios were prepared, and three chitosan addition methods were adopted to investigate the effect on the surface and interface properties of calcium sulfate/chitosan composite bone cement. The results showed that it lacked chemical bond between chitosan and calcium sulfate, and the short rod calcium sulfate displayed better interface adhesion with chitosan owing to its smaller size, so it possessed shorter setting time, better compressive strength and slower degradation than the long rod calcium sulfate, while the biocompatibility had no remarkable difference. Moreover, chitosan solution as liquid phase was a better solidification mode than citric acid, and calcium sulfate/chitosan composite as solid phase was the worst mode because of poor interface compatibility. Conclusively, it was a simple, low‐cost, and effective preparation process to choose short rod calcium sulfate powder as solid phase and 1 wt% chitosan solution as liquid phase, which could achieve calcium sulfate/chitosan composite bone cement with the best properties, including setting time, compressive strength, degradation rate, and biocompatibility, displaying a promising application in bone defect repair. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2769-643X |
| Relation: | https://doaj.org/toc/2769-643X |
| DOI: | 10.1002/mba2.99 |
| URL الوصول: | https://doaj.org/article/030c46beff3d41fa84e2059072146e60 |
| رقم الانضمام: | edsdoj.030c46beff3d41fa84e2059072146e60 |
| قاعدة البيانات: | Directory of Open Access Journals |
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