Academic Journal
No effect of test and treat on sexual behaviours at population level in rural South Africa
| العنوان: | No effect of test and treat on sexual behaviours at population level in rural South Africa |
|---|---|
| المؤلفون: | Rolland, M, McGrath, N, Tiendrebeogo, T, Larmarange, J, Pillay, D, Dabis, F, Orne-Gliemann, J, ANRS 12249 TasP study group, . |
| المصدر: | AIDS , 33 (4) pp. 709-722. (2019) |
| سنة النشر: | 2019 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | Africa, antiretroviral therapy, HIV, prevention, sexual behaviour |
| الوصف: | CONTEXT: Within the community-randomised ANRS 12249 Treatment-as-Prevention (TasP) trial conducted in rural South Africa, we analysed sexual behaviours stratified by sex over time, comparing immediate ART irrespective of CD4 count vs CD4-guided ART (start at CD4>350 then >500) arms. METHODS: As part of the 6-monthly home-based trial rounds, a sexual behaviour questionnaire (IQ) was administered to all residents ≥16 years. We considered seven indicators: sexual intercourse in the past month; at least one regular sexual partner in the past six months; at least one casual sexual partner in the past six months and more than one sexual partner in the past six months; condom use at last sex (CLS) with regular partner, CLS with casual partner, and point prevalence estimate of concurrency. We conducted repeated cross-sectional analyses, stratified by sex. GEE models were used, including trial arm, trial time, calendar time and interaction between trial arm and trial time. RESULTS: CLS with regular partner varied between 29%-51% and 23%- 46% for men and women, respectively, with significantly lower odds among women in the control versus intervention arm by trial end (p < 0.001). CLS with casual partner among men showed a significant interaction between arm and trial round, with no consistent pattern. Women declared more than one partner in the past 6 months in less that 1% of IQs; among men, rates varied between 5%-12%, and odds significantly and continuously declined between calendar rounds 1 and 7 (OR = 4.2 [3.24-5.45]). CONCLUSION: Universal Test and Treat was not associated with increased sexual risk behaviours. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | https://discovery.ucl.ac.uk/id/eprint/10065906/1/No_effect_of_test_and_treat_on_sexual_behaviours.97016.pdf; https://discovery.ucl.ac.uk/id/eprint/10065906/ |
| الاتاحة: | https://discovery.ucl.ac.uk/id/eprint/10065906/1/No_effect_of_test_and_treat_on_sexual_behaviours.97016.pdf https://discovery.ucl.ac.uk/id/eprint/10065906/ |
| Rights: | open |
| رقم الانضمام: | edsbas.F12C83 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |