Academic Journal
Associations between air pollutants and blood pressure in an ethnically diverse cohort of adolescents in London, England
| العنوان: | Associations between air pollutants and blood pressure in an ethnically diverse cohort of adolescents in London, England |
|---|---|
| المؤلفون: | Karamanos, A, Lu, Y, Mudway, I S, Ayis, S, Kelly, F J, Beevers, S D, Dajnak, D, Fecht, D, Elia, C, Tandon, S, Webb, A J, Grande, A J, Molaodi, O R, Maynard, M J, Cruickshank, J K, Harding, S |
| المصدر: | Karamanos , A , Lu , Y , Mudway , I S , Ayis , S , Kelly , F J , Beevers , S D , Dajnak , D , Fecht , D , Elia , C , Tandon , S , Webb , A J , Grande , A J , Molaodi , O R , Maynard , M J , Cruickshank , J K & Harding , S 2023 , ' Associations between air pollutants and blood pressure in an ethnically diverse cohort of adolescents in London, England ' , PLoS ONE , vol. 18 , .... |
| سنة النشر: | 2023 |
| المجموعة: | King's College, London: Research Portal |
| مصطلحات موضوعية: | Male, Female, Humans, Adolescent, Child, Air Pollutants/adverse effects, Blood Pressure, Nitrogen Dioxide/analysis, London, Ethnicity, Environmental Exposure/adverse effects, Minority Groups, Air Pollution/adverse effects, Particulate Matter/adverse effects, Ozone/adverse effects, England/epidemiology |
| الوصف: | Longitudinal evidence on the association between air pollution and blood pressure (BP) in adolescence is scarce. We explored this association in an ethnically diverse cohort of schoolchildren. Sex-stratified, linear random-effects modelling was used to examine how modelled residential exposure to annual average nitrogen dioxide (NO2), particulate matter (PM2.5, PM10) and ozone (O3), measures in μg/m3, associated with blood pressure. Estimates were based on 3,284 adolescents; 80% from ethnic minority groups, recruited from 51 schools, and followed up from 11-13 to 14-16 years old. Ethnic minorities were exposed to higher modelled annual average concentrations of pollution at residential postcode level than their White UK peers. A two-pollutant model (NO2 & PM2.5), adjusted for ethnicity, age, anthropometry, and pubertal status, highlighted associations with systolic, but not diastolic BP. A μg/m3 increase in NO2 was associated with a 0.30 mmHg (95% CI 0.18 to 0.40) decrease in systolic BP for girls and 0.19 mmHg (95% CI 0.07 to 0.31) decrease in systolic BP for boys. In contrast, a 1 μg/m3 increase in PM2.5 was associated with 1.34 mmHg (95% CI 0.85 to 1.82) increase in systolic BP for girls and 0.57 mmHg (95% CI 0.04 to 1.03) increase in systolic BP for boys. Associations did not vary by ethnicity, body size or socio-economic advantage. Associations were robust to adjustments for noise levels and lung function at 11-13 years. In summary, higher ambient levels of NO2 were associated with lower and PM2.5 with higher systolic BP across adolescence, with stronger associations for girls. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://kclpure.kcl.ac.uk/portal/en/publications/35d2be4a-e1f6-44d3-82d1-a320ddeec4ca |
| DOI: | 10.1371/journal.pone.0279719 |
| الاتاحة: | https://kclpure.kcl.ac.uk/portal/en/publications/35d2be4a-e1f6-44d3-82d1-a320ddeec4ca https://doi.org/10.1371/journal.pone.0279719 http://www.scopus.com/inward/record.url?scp=85147783497&partnerID=8YFLogxK |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.ED9B1500 |
| قاعدة البيانات: | BASE |
كن أول من يترك تعليقا!