Academic Journal
Synthetic condensate size correlates with yeast replicative cell age
| العنوان: | Synthetic condensate size correlates with yeast replicative cell age |
|---|---|
| المؤلفون: | Heidenreich, Meta, Georgeson, Joseph M., Nadav, Yotam, Levy, Emmanuel |
| المصدر: | ISSN: 2578-9430 ; microPublication biology, (2022. |
| سنة النشر: | 2022 |
| المجموعة: | Université de Genève: Archive ouverte UNIGE |
| الوصف: | We recently developed a synthetic protein based system that forms condensates in vivo (Heidenreich et al. 2020). The system consists of two proteins that interact and condense into a round, mesh-like structure. The structures grow over time, since the components are constitutively expressed. This hints that condensate size could be used as a molecular timer. Here, we show that such a system indeed serves as a good proxy for yeast's replicative age. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/35673323; https://archive-ouverte.unige.ch/unige:176889; unige:176889 |
| الاتاحة: | https://archive-ouverte.unige.ch/unige:176889 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.E27DC541 |
| قاعدة البيانات: | BASE |
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