Academic Journal
Viruses and bacteria in acute asthma exacerbations - A GA(2) LEN-DARE* systematic review
| العنوان: | Viruses and bacteria in acute asthma exacerbations - A GA(2) LEN-DARE* systematic review |
|---|---|
| المؤلفون: | Papadopoulos, N G, Christodoulou, I, Rohde, G, Agache, I, Almqvist, C, Bruno, A, Bonini, S, Bont, L, Bossios, A, Bousquet, J, Braido, F, Brusselle, G, Canonica, G W, Carlsen, K H, Chanez, P, Fokkens, W J, Garcia-Garcia, M, Gjomarkaj, M, Haahtela, T, Holgate, S T, Johnston, S L, Konstantinou, G, Kowalski, Marcin Ryszard, Lewandowska-Polak, A, Lødrup-Carlsen, K, Mäkelä, Marjukka, Malkusova, I, Mullol, J, Nieto, A, Eller, Esben, Ozdemir, C, Panzner, P, Popov, T, Psarras, S, Roumpedaki, E, Rukhadze, M, Stipic-Markovic, A, Todo Bom, A, Toskala, E, Van Cauwenberge, P, Van Drunen, C, Watelet, J B, Xatzipsalti, M, Xepapadaki, P, Zuberbier, T |
| المصدر: | Papadopoulos , N G , Christodoulou , I , Rohde , G , Agache , I , Almqvist , C , Bruno , A , Bonini , S , Bont , L , Bossios , A , Bousquet , J , Braido , F , Brusselle , G , Canonica , G W , Carlsen , K H , Chanez , P , Fokkens , W J , Garcia-Garcia , M , Gjomarkaj , M , Haahtela , T , Holgate , S T , Johnston , S L , Konstantinou , G , Kowalski , M R , .... |
| سنة النشر: | 2011 |
| المجموعة: | University of Southern Denmark: Research Output / Syddansk Universitet |
| الوصف: | To cite this article: Papadopoulos NG, Christodoulou I, Rohde G, Agache I, Almqvist C, Bruno A, Bonini S, Bont L, Bossios A, Bousquet J, Braido F, Brusselle G, Canonica GW, Carlsen KH, Chanez P, Fokkens WJ, Garcia-Garcia M, Gjomarkaj M, Haahtela T, Holgate ST, Johnston SL, Konstantinou G, Kowalski M, Lewandowska-Polak A, Lødrup-Carlsen K, Mäkelä M, Malkusova I, Mullol J, Nieto A, Eller E, Ozdemir C, Panzner P, Popov T, Psarras S, Roumpedaki E, Rukhadze M, Stipic-Markovic A, Todo Bom A, Toskala E, van Cauwenberge P, van Drunen C, Watelet JB, Xatzipsalti M, Xepapadaki P, Zuberbier T. Viruses and bacteria in acute asthma exacerbations - A GA(2) LEN-DARE systematic review. Allergy 2010; DOI:10.1111/j.1398-9995.2010.02505.x. ABSTRACT: A major part of the burden of asthma is caused by acute exacerbations. Exacerbations have been strongly and consistently associated with respiratory infections. Respiratory viruses and bacteria are therefore possible treatment targets. To have a reasonable estimate of the burden of disease induced by such infectious agents on asthmatic patients, it is necessary to understand their nature and be able to identify them in clinical samples by employing accurate and sensitive methodologies. This systematic review summarizes current knowledge and developments in infection epidemiology of acute asthma in children and adults, describing the known impact for each individual agent and highlighting knowledge gaps. Among infectious agents, human rhinoviruses are the most prevalent in regard to asthma exacerbations. The newly identified type-C rhinoviruses may prove to be particularly relevant. Respiratory syncytial virus and metapneumovirus are important in infants, while influenza viruses seem to induce severe exacerbations mostly in adults. Other agents are relatively less or not clearly associated. Mycoplasma and Chlamydophila pneumoniae seem to be involved more with asthma persistence rather than with disease exacerbations. Recent data suggest that common bacteria may also be involved, but this ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://portal.findresearcher.sdu.dk/da/publications/94b2699c-fa5d-4eb6-bf17-00b2bcc34bb8 |
| DOI: | 10.1111/j.1398-9995.2010.02505.x |
| الاتاحة: | https://portal.findresearcher.sdu.dk/da/publications/94b2699c-fa5d-4eb6-bf17-00b2bcc34bb8 https://doi.org/10.1111/j.1398-9995.2010.02505.x |
| Rights: | info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.C511CA8 |
| قاعدة البيانات: | BASE |
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