Academic Journal

Seroprevalence of Anti-SARS-CoV-2 Antibodies in Blood Donors from Nuevo Leon State, Mexico, during 2020: A Retrospective Cross-Sectional Evaluation

التفاصيل البيبلوغرافية
العنوان: Seroprevalence of Anti-SARS-CoV-2 Antibodies in Blood Donors from Nuevo Leon State, Mexico, during 2020: A Retrospective Cross-Sectional Evaluation
المؤلفون: Natalia Martinez-Acuña, Diana Minerva Avalos-Nolazco, Diana Raquel Rodriguez-Rodriguez, Cynthia Gabriela Martinez-Liu, Kame Alberto Galan-Huerta, Gerardo Raymundo Padilla-Rivas, Javier Ramos-Jimenez, Sergio Ayala-de-la-Cruz, Eduardo Cienfuegos-Pecina, Erik Alejandro Diaz-Chuc, Rogelio Cazares-Tamez, Amador Flores-Arechiga, Fernando Perez-Chavez, Daniel Arellanos-Soto, Sonia Amelia Lozano-Sepulveda, Elvira Garza-Gonzalez, Consuelo Treviño-Garza, Roberto Montes-de-Oca-Luna, Aurora Beatriz Lee-Gonzalez, Manuel Enrique de-la-O-Cavazos, Ana Maria Rivas-Estilla
المصدر: Viruses; Volume 13; Issue 7; Pages: 1225
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2021
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: blood donors, COVID-19, anti-SARS-CoV-2 IgG, seroprevalence, Mexico
جغرافية الموضوع: agris
الوصف: The progression and distribution of the SARS-CoV-2 pandemic are continuously changing over time and can be traced by blood donors’ serological survey. Here, we investigated the seroprevalence of anti-SARS-CoV-2 antibodies in blood donors in Nuevo Leon, Mexico during 2020 as a strategy for the rapid evaluation of the spread of SARS-CoV-2 and asymptomatic case detection. We collected residual plasma samples from blood donors who attended two regional donation centers from January to December of 2020 to identify changes in anti-SARS-CoV-2 IgG prevalence. Plasma samples were analyzed on the Abbott Architect instrument using the commercial Abbott SARS-CoV-2 IgG chemiluminescent assay. We found a total of 99 reactive samples from 2068 analyzed plasma samples, resulting in a raw prevalence of 4.87%. Donors aged 18–49 years were more likely to be seropositive compared to those aged >50 years (p < 0.001). Weekly seroprevalence increased from 1.8% during the early pandemic stage to 27.59% by the end of the year. Prevalence was 1.46-fold higher in females compared to males. Case geographical mapping showed that Monterrey city recorded the majority of SARS-CoV-2 cases. These results show that there is a growing trend of seroprevalence over time associated with asymptomatic infection that is unnoticed under the current epidemiological surveillance protocols.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: SARS-CoV-2 and COVID-19; https://dx.doi.org/10.3390/v13071225
DOI: 10.3390/v13071225
الاتاحة: https://doi.org/10.3390/v13071225
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.C03592CD
قاعدة البيانات: BASE